Polyvinyl Alcohol (PVA) Coated Capillaries
PVA-coated capillaries contain a permanently adsorbed layer of polyvinyl alcohol. This coating minimizes hydrophobic and electrostatic solute/wall interactions and eliminates electroosmotic flow (EOF). Many proteins and amines can be analyzed without the peak tailing found with uncoated capillaries. In addition, since EOF is eliminated, cumbersome washing procedures are unnecessary and migration time reproducibility can be improved.