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Publication

Plumbagin Elicits Cell-Specific Cytotoxic Effects and Metabolic Responses in Melanoma Cells

Journal: Pharmaceutics
Publication Date: 12 May 2021
Author: Zhang H , et al.

Quick View Supporting Products

Authors	Zhang H, Zhang, A, Gupte, AA and Hamilton, DJ
Journal	Pharmaceutics
Publication Date	12 May 2021
Research Area(s) include	Cancer Research, Drug Discovery
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XF 96 well (XF Pro/XFe96/XF96)
Mode	N/A
Cell Line(s) include	A375, Melanoma cells, SK-MEL-28
Cell Type(s) include	Melanoma cells
Species	Human
Assay / Method	Cell Mitochondrial Stress Test, Real-Time ATP Rate Assay
Cell Seeding Density	2.0x10^4 cells/well
Plate Coating	Not Specified

Authors	Gibb AA, Lorkiewicz PK, Zheng YT, Zhang X, Bhatnagar A, Jones SP, Hill BG
Journal	Biochem J
Publication Date	13 July 2017
Research Area(s) include	Cardiovascular Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	Cardiomyocytes
Cell Type(s) include	Cardiac cells
Species	Rat
Assay / Method	Cell Mitochondrial Stress Test
Cell Seeding Density	7.5x10^4 cells/well
Plate Coating	Not Specified

Authors	de Carvalho A, Bassaneze V, Forni MF, Keusseyan AA, Kowaltowski AJ, Krieger JE
Journal	Sci Rep
Publication Date	13 Nov 2017
Research Area(s) include	Cardiovascular Research, Stem Cell Biology
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	Cardiomyocytes
Cell Type(s) include	Cardiac cells
Species	Rat
Assay / Method	Cell Mitochondrial Stress Test
Cell Seeding Density	4.0x10^4 cells/well
Plate Coating	Not Specified

Authors	Bruzzaniti S, Bocchino M, Santopaolo M, Cali G, Stanziola AA, D'Amato M, Esposito A, Barra E, Garziano F, Micillo T, Zuchegna C, Romano A, De Simone S, Zuccarelli B, Mottola M, De Rosa V, Porcellini A, Perna F, Matarese G, and Galgani M
Journal	Proc Natl Acad Sci U S A
Publication Date	30 July 2019
Research Area(s) include	Cardiovascular Research, Immunology Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XF 96 well (XF Pro/XFe96/XF96)
Cell Line(s) include	T-cells
Cell Type(s) include	Immune cells
Species	Human
Assay / Method	Cell Mitochondrial Stress Test
Cell Seeding Density	4.0x10^5 cells/well
Plate Coating	Not Specified

Authors	Untereiner AA, Olah G, Modis K, Hellmich MR, Szabo C
Journal	Biochem Pharmacol
Publication Date	09 Apr 2017
Research Area(s) include	Cancer Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	HCT116
Cell Type(s) include	Colon cancer cells
Species	Human
Assay / Method	Cell Mitochondrial Stress Test, Glycolysis Stress Test
Cell Seeding Density	Not Specified
Plate Coating	Not Specified

Authors	Guieze R, Liu VM, Rosebrock D, Jourdain AA, Hernandez-Sanchez M, Martinez Zurita A, Sun J, Ten Hacken E, Baranowski K, Thompson PA, Heo JM, Cartun Z, Aygun O, Iorgulescu JB, Zhang W, Notarangelo G, Livitz D, Li S, Davids MS, Biran A, Fernandes SM, Brown JR, Lako A, Ciantra ZB, Lawlor MA, Keskin DB, Udeshi ND, Wierda WG, Livak KJ, Letai AG, Neuberg D, Harper JW, Carr SA, Piccioni F, Ott CJ, Leshchiner I, Johannessen CM, Doench J, Mootha VK, Getz G, and Wu CJ
Journal	Cancer Cell
Publication Date	14 Oct 2019
Research Area(s) include	Cancer Research, Immunology Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XF 96 well (XF Pro/XFe96/XF96)
Cell Line(s) include	OCI-Ly, SU-DHL4
Cell Type(s) include	Leukemia cells
Species	Human
Assay / Method	Cell Mitochondrial Stress Test
Cell Seeding Density	1.25x10^5 cells/well, 5.0x10^5 cells/well
Plate Coating	Not Specified

Authors	Mookerjee SA, Gerencser AA, Nicholls DG, Brand MD
Journal	J Biol Chem
Publication Date	28 Apr 2017
Research Area(s) include	Techniques and Methods
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	C2C12
Cell Type(s) include	Myoblasts
Species	Mouse
Assay / Method	Cell Mitochondrial Stress Test, Glycolysis Stress Test
Cell Seeding Density	2.5x10^4 cells/well
Plate Coating	Not Specified

Authors	Flynn JM, Choi SW, Day NU, Gerencser AA, Hubbard A, Melov S
Journal	Free Radic Biol Med
Publication Date	01 Apr 2011
Research Area(s) include	Neurobiology Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	Cortical Synaptosomes
Cell Type(s) include	Neuronal cells
Species	Mouse
Assay / Method	Cell Mitochondrial Stress Test
Cell Seeding Density	10 µg protein/well
Plate Coating	PEI (1:15000)

Authors	Salabei JK, Gibb AA, Hill BG
Journal	Nat Protoc
Publication Date	01 Feb 2014
Research Area(s) include	Cell Physiology Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	Rat Aortic Smooth Muscle Cells (RASMC)
Cell Type(s) include	Cardiac cells
Species	Rat
Assay / Method	Cell Mitochondrial Stress Test, Substrate Utilization
Cell Seeding Density	4.0-5.0x10^4 cells/well
Plate Coating	Not Specified

Authors	Untereiner AA, Pavlidou A, Druzhyna N, Papapetropoulos A, Hellmich MR, Szabo C
Journal	Biochem Pharmacol
Publication Date	20 Oct 2017
Research Area(s) include	Cancer Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	HCT116
Cell Type(s) include	Colon cancer cells
Species	Human
Assay / Method	Cell Mitochondrial Stress Test, Glycolysis Stress Test
Cell Seeding Density	Not Specified
Plate Coating	Not Specified

Authors	Salabei JK, Lorkiewicz PK, Mehra P, Gibb AA, Haberzettl P, Hong KU, Wei X, Zhang X, Li Q, Wysoczynski M, Bolli R, Bhatnagar A, Hill BG
Journal	J Biol Chem
Publication Date	01 May 2016
Research Area(s) include	Cardiovascular Research, Obesity, Diabetes, and Metabolic Disorders
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	Cardiac progenitor cells
Cell Type(s) include	Cardiac cells
Species	Mouse
Assay / Method	Cell Mitochondrial Stress Test, Substrate Utilization
Cell Seeding Density	Not Specified
Plate Coating	Not Specified

Authors	Wettersten HI, Hakimi AA, Morin D, Bianchi C, Johnstone ME, Donohoe DR, Trott JF, Abu Aboud O, Stirdivant S, Neri B, Wolfert R, Stewart B, Perego R, Hsieh JJ, Weiss RH
Journal	Cancer Res
Publication Date	01 May 2015
Research Area(s) include	Cancer Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	786-O, Caki-1, Epithelial cells
Cell Type(s) include	Kidney cells, Renal Cell Carcinoma
Species	Human
Assay / Method	Fatty Acid Oxidation, Substrate Utilization
Cell Seeding Density	Not Specified
Plate Coating	Not Specified

Authors	van Dam AD, Nahon KJ, Kooijman S, van den Berg SM, Kanhai AA, Kikuchi T, Heemskerk MM, van Harmelen V, Lombès M, van den Hoek AM, de Winther MP, Lutgens E, Guigas B, Rensen PC, Boon MR
Journal	Diabetes
Publication Date	01 Dec 2014
Research Area(s) include	Obesity, Diabetes, and Metabolic Disorders
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XF 96 well (XF Pro/XFe96/XF96)
Cell Line(s) include	T37i
Cell Type(s) include	Adipocytes
Species	Mouse
Assay / Method	Substrate Utilization
Cell Seeding Density	Not Specified
Plate Coating	Not Specified

Authors	Mookerjee SA, Goncalves RL, Gerencser AA, Nicholls DG, Brand MD
Journal	Biochim Biophys Acta
Publication Date	01 Feb 2015
Research Area(s) include	Cell Physiology Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	C2C12, Isolated mitochondria
Cell Type(s) include	Isolated mitochondria, Myoblasts
Species	Mouse, Rat
Assay / Method	Substrate Utilization
Cell Seeding Density	2.0x10^4 cells/well, Not Specified
Plate Coating	Not Specified

Authors	Gerencser AA
Journal	Biochim Biophys Acta Bioenerg
Publication Date	08 June 2018
Research Area(s) include	Cell Physiology Research, Obesity, Diabetes, and Metabolic Disorders
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XF 96 well (XF Pro/XFe96/XF96)
Cell Line(s) include	Islets
Cell Type(s) include	Pancreatic cells
Species	Human
Assay / Method	Other
Cell Seeding Density	1.7x10^4 cells/well
Plate Coating	Polyethyleneimine (PEI)

Authors	Zhang X, Espinosa B, Saei AA, D'Arcy P, Zubarev RA, and Linder S
Journal	Oxid Med Cell Longev
Publication Date	10 June 2019
Research Area(s) include	Cancer Research, Drug Discovery
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XFe24/XF24
Cell Line(s) include	HCT116
Cell Type(s) include	Colon cancer cells
Species	Human
Assay / Method	Other
Cell Seeding Density	6.0x10^4 cells/well
Plate Coating	Not Specified

Authors	Jiang L, Shestov AA, Swain P, Yang C, Parker SJ, Wang QA, Terada LS, Adams ND, McCabe MT, Pietrak B, Schmidt S, Metallo CM, Dranka BP, Schwartz B, DeBerardinis RJ
Journal	Nature
Publication Date	01 Apr 2016
Research Area(s) include	Cancer Research
Technique	Seahorse XF Technology
Analyzer(s) include	Seahorse XF 96 well (XF Pro/XFe96/XF96), Seahorse XFe24/XF24
Cell Line(s) include	H460
Cell Type(s) include	Lung cancer cells
Species	Human
Assay / Method	Basal Metabolic Assay
Cell Seeding Density	3.0x10^4 cells/well, Not Specified
Plate Coating	Not Specified