MassHunter for GC/MS

Image Not Available

Integrated instrument control, data acquisition, and analysis across GC/MS platforms

  • MassHunter Acquisition Software for GC/MS Systems allows straightforward control of your Agilent GC/MS MSD, triple quadrupole (TQ), and quadrupole time-of-flight (Q-TOF) GC/MS systems. It also controls the latest gas chromatography technologies, including innovative sampling techniques and dedicated GC detectors. MassHunter Acquisition for GC/MS 14.0 is the latest software that controls the new 5987A GC/MSD with newly integrated features like Optimizer, dynamic SIM (dSIM) simultaneous dSIM/Scan etc.
  • This data acquisition software for GC/MS unlocks the full potential of Agilent GC/MS systems in your lab by providing intuitive access to mass spectrometry. Capabilities like automated tuning and optimization allow easy instrument and method setup. Curated application focused libraries allow to automatically identify targeted and untargeted analytes.
  • MassHunter Acquisition14 for single quad MS and MassHunter Acquisition 13 for triple quad and QTOF MS provide a platform across all GC/MS systems
  • Optimizer to simplify development of SIM methods for single quads and MRM for triple quads, seamlessly optimizes isolation windows, collision energies, and transitions using existing GC methods
  • Dynamic SIM and dynamic MRM remove the constraints of time segments to optimize detection for each peak, monitor more ions and greatly simplifies method complexity
  • Simultaneous dSIM/Scan combining quantitation method and full scan to perform retrospective analysis without the need for reinjection
  • Importing worklists from spreadsheets saves time in method development and high throughput screening
  • Streamlined retention time locking interface housed within MassHunter Acquisition improves usability
  • Built-in technical controls combined with procedural controls ensure the security of your data, control access, and facilitate compliance as defined by U.S. FDA 21 CFR Part 11, EU Annex 11, and similar national electronic record regulations
  • Scheduling of ion source features like Agilent JetClean, which can reduce frequency of cleaning cycles when used while samples are being acquired, or during offline cleaning mode
  • Easy SamplePrep technology simplifies automation of sample introduction via Agilent&#146s extensive autosampler technologies
  • Maximized uptime and planned maintenance with Early Maintenance Feedback (EMF) that aligns and monitors GC/MS operations

Overview

Specifications

Applications

The Agilent MassHunter Optimizer for GC/TQ

MassHunter Optimizer for GC/TQ is compatible with the 7000 and 7010 series triple quadrupole GC/MS (GC/TQ). The tool automates MRM method development and enables a smooth transition from single quadrupole GC/MSD methods to GC/TQ for significant time savings and increased productivity. Automated parameter optimization includes precursor and product ion identification and selection of various collision energies. Workflows like Start from Scan Data, SIM Ions, or MRMs enable a streamlined process that provides precise and reproducible results.

Watch step-by-step method setup

optimizer-gc-tq-960x540-agilent.jpg
Masshunter-autotune-gcms-GD__3142-960x540-agilent

Automated and manual tuning with MassHunter acquisition software for GC/MS

Autotune is the best choice for applications that require the highest performance across the entire scan range. The instrument is calibrated for maximized sensitivity for three major ion fragments distributed within the scan range. Alternatively, manual tune can be used to increase sensitivity for a narrower mass range. Also, Agilent GC/MSDs allow for automated bromofluorobenzene (BFB) and decafluorotriphenylphosphine (DFTPP) target tuning to meet specific ion ratio criteria set by U.S. EPA methods for volatiles and semivolatiles analysis.

Training & events

Agilent University

Develop skills and improve lab productivity with a wide variety of learning options from Agilent Education.

webinarType
Events

News

Agilent Launches New GC Systems with GC Assist to Improve Laboratory Efficiency and Data Quality

Agilent Technologies has launched the 8890B and 8860B GC systems featuring GC Assist, new instrument intelligence offering system monitoring, built-in troubleshooting, and secure remote connectivity. Designed to reduce downtime, improve data quality, and boost efficiency, the systems add an oven light, onboard maintenance videos, and dual simultaneous injections; the 8890B also supports up to four detectors and 30% faster oven cooling. GC Assist flags quality control issues, monitors gas usage and leaks, and guides maintenance.

26 May 2026

Agilent Launches 5987A MSD with GC Assist

Agilent Technologies has launched the 5987A single quadrupole mass selective detector with GC Assist and MassHunter Acquisition14 software. Paired with the 8890B or 8860B GC, it forms an integrated GC/MS system that improves data quality and reduces unplanned downtime. The 5987A offers up to 25% faster scan rates, enabling dSIM and simultaneous dSIM/Scan modes, while Optimizer automates SIM method development. GC Assist monitors over 60 system parameters, flags quality control issues, guides maintenance, and supports remote troubleshooting within secure networks.

02 Nov 2026

Need help? Contact our support team