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GPC & SEC columns & standards for polymer & plastic analysis in aqueous, organic, and polar solvents.

Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for decades. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules.

SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz). GPC/SEC columns can be used with organic, aqueous, and polar solvents. GPC/SEC columns offered include PLgel, PL aquagel-OH, PolarGel, SUPREMA, NOVEMA Max, and GRAM.

Manufactured using ISO 9001 certification, GPC/SEC standards are traceable with a unique batch number and a certificate of analysis.

The 2022 acquisition of Polymer Standards Service (PSS) expanded Agilent's offerings for gel permeation chromatography (GPC) and size exclusion chromatography (SEC) polymer analysis. The acquisition broadened Agilent’s portfolio and offerings for the analysis of natural and synthetic polymers, including both GPC and SEC columns and standards.

GPC/SEC Columns & Standards

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Featured Tools

GPC/SEC Column Selector Tools

A series of tools to help you navigate to the best GPC/SEC column choice for your application.

Bio HPLC Columns eSelector Tools

Intuitive process to help you select the right chromatography column for your biopharmaceutical applications.

LC Application Finder

Search for GPC/SEC Application Notes and Technical Overviews

Featured Literature

Agilent GPC/SEC Columns and Standards Portfolio Brochure

Improve GPC/SEC analysis of macromolecules -- or develop new applications for challenging polar and/or charged macromolecules -- using Agilent columns, standards, instrumentation, software and services.

Seamless Solutions for Any Macromolecular Analysis Needs

Whatever your GPC/SEC needs, Agilent has you covered. Discover our comprehensive range of integrated solutions and services for macromolecular analysis.

Analysis of mRNA-Lipid Nanoparticles in Human Plasma using SEC-Static Dual-Angle Light Scattering and RI Detection

This application note describes the use of size exclusion chromatography with a multidetector system for the study of lipid nanoparticles in human plasma.

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Featured News

Agilent Launches New GPC/SEC Columns Selector Tools

The GPC/SEC Columns Selector Tools help you navigate to the best GPC/SEC column choice for your application. Guidance can be by mobile phase, application, manufacturer’s part number cross-reference, USP designation, or EP monograph.

New Comprehensive GPC/SEC Solutions Introduced at HPLC 2023 Conference

Agilent showcased significantly expanded InfinityLab GPC/SEC Solution at the HPLC 2023 conference on June 18 – 22, 2023 in Düsseldorf, Germany. The Agilent InfinityLab GPC/SEC portfolio became even more comprehensive after the recent acquisition of Polymer Standard Service Ltd. (PSS), including a dedicated GPC/SEC Column Thermostat, a Multi-Angle Light Scattering Detector, the GPC/SEC-Ready Kit, and the powerful WinGPC Software into the already existing InfinityLab GPC/SEC Solutions for advanced material characterization.

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