SurePrint G3 Pre/Postnatal and cancer Baylor Microarrays
The Agilent Pre/Postnatal and cancer research CGH & CGH+SNP Microarrays are dual-color microarrays containing 60-mer oligonucleotides designed and optimized by Baylor College of Medicine experts to target regions relevant to these areas of research. We provide different formats to accommodate resolution and throughput. These microarrays are designed with genome-wide backbone probes and increased resolution, down to exon level, in relevant regions.
The Baylor cancer research array has dense probe coverage in over 2,300 exon-by-exon in cancer focused genes with known cancer association. The postnatal design have extra focus in relevant regions for postnatal cytogenetic research, with 1,700 selected genes with exon-by-exon coverage with 6 probes per exon to detect more disease relevant aberrations, while prenatal design focus on cytogenetically relevant microdeletions, microduplications, known disease genes, pericentromeric and subtelomeric regions.
The Baylor cancer research array has dense probe coverage in over 2,300 exon-by-exon in cancer focused genes with known cancer association. The postnatal design have extra focus in relevant regions for postnatal cytogenetic research, with 1,700 selected genes with exon-by-exon coverage with 6 probes per exon to detect more disease relevant aberrations, while prenatal design focus on cytogenetically relevant microdeletions, microduplications, known disease genes, pericentromeric and subtelomeric regions.
For Research Use Only. Not for use in diagnostic procedures.
Product Details
Features
- The probe design and selection have been carefully optimized and validated for maximal sensitivity and specificity
- Target regions have been identified by Baylor College of Medicine experts
- Increased coverage in known disease-gene regions with up to 6 probes per exon to detect more disease relevant aberrations
- Agilent provides validated protocols and reagents to process fresh frozen DNA (SureTag DNA Labeling Kit) and degraded or FFPE samples (ULS Labeling Kit)
- The microarray contains internal quality control features to ensure accurate results
- Microarrays are made to order. Please check with your Agilent representative for lead time
Featured References
- Publications
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- Chromosomal microarray analysis of Bulgarian patients with epilepsy and intellectual disability. Peycheva V, Kamenarova K, Ivanova N, Stamatov D, Avdjieva-Tzavella D, Alexandrova I, Zhelyazkova S, Pacheva I, Dimova P, Ivanov I, Litvinenko I, Bozhinova V, Tournev I, Simeonov E, Mitev V, Jordanova A, Kaneva, R. Gene. 2018 Aug 15;667:45-55. doi: 10.1016/j.gene.2018.05.015. Epub 2018 May 9. [Application: Postnatal] Learn More
- Pinto D et al. Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants. Nat Biotechnol. 2011 May 8;29(6):512-20. doi: 10.1038/nbt.1852 [Application: General] Learn More
- Alesi V et al. Easychip 8x15k: A New Tool for Detecting Chromosome Anomalies in Low Risk Pregnancies, Supporting and Integrating Standard Karyotype J Genet Syndr Gene Ther 7: 277. doi:10.4172/2157-7412.1000277 [Application: Prenatal] Learn More
- Chau MHK et al. Characteristics and mode of inheritance of pathogenic copy number variants in prenatal diagnosis. Am J Obstet Gynecol. 2019 Nov;221(5):493.e1-493.e11. doi: 10.1016/j.ajog.2019.06.007. Epub 2019 Jun 14. [Application: Prenatal] Learn More
