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PRESENTATION
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Many environmental and host-associated microbes grow forming biofilms. The high resistance to conventional antimicrobials of bacterial and fungal biofilms imposes a significant threat to human health, making the understanding, study and treatment of biofilms extremely challenging. Unlike standard biofilm methodologies, impedance techniques offer a label-free, real-time approach to monitoring biofilm growth and treatment responses.
In this webinar, Dr. Alex Mira focuses on the potential of impedance-based measurements to advance current knowledge on microbial biofilms. He describes how it can be used to quantify biofilm growth and to study biofilm dynamics in pure cultures of yeasts and Gram-positive and Gram-negative bacteria, as well as complex, multispecies biofilms like dental plaque. In addition, different research applications of the technology in microbiology will also be discussed, including: 1) understanding biofilm biology; 2) testing novel antimicrobial compounds; 3) detecting persister cells; 4) performing antibiotic susceptibility testing; and 5) improving antibiotic selection in clinical research settings.
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