To bake out the LC/MS perform the following

1. Connect the LC/MSD inlet tubing (p/n 0890-1915).
2. Select the Tune view.
3. Select Tune > Manual Tune
4. Display the MS Tune Spray Chamber dialog box.
5. Set the drying gas flow to 7 L/min for MM-ES or 5 L/min for MM-ES+APCI or MM-APCI.
6. Set the nebulizer pressure to 40 psi.
7. Set the drying gas temperature to 300 °C.
8. Set the vaporizer temperature to 250 °C. (MM-ES+APCI or MM-APCI only)
9. Set the LC flow to 0.5 mL/min using the solvent mixture appropriate for your instrument model. Refer to the section To determine proper solvent mixture for performance verification on page 27 for more information.
10. If you are doing performance verification on G1956B or G1946D LC/MSD SL model only - Install the 2.1 x 30mm x 3.5 micron B-C18 Rapid Resolution column.
11. Make sure the position of the MS selection valve is set so that the LC flow is diverted to the spray chamber (select Switch Stream > MSD)
12. Allow the system to bake out for at least 2 hours.