ABSTRACT In this webinar, Dr. George Rogers will introduce the new Agilent Seahorse XF Substrate Oxidation Stress Tests, a robust portfolio of XF assays enabling critical insights into cellular substrate dependencies to identify specific mitochondrial substrates that are relevant for cellular phenotype and function. Understanding substrate dependencies is critical for advancing therapeutic opportunities across a range of diseases, and investigation of the components that modulate metabolism is a promising avenue for developing novel pharmaceutical targets. Emerging evidence demonstrates that metabolites themselves, including the oxidation of specific mitochondrial substrates, can drive cell function and phenotype with respect to proliferation, differentiation, as well as dysfunction/disease.

WHAT YOU WILL LEARN
  • An overview of XF Substrate Oxidation Stress Test assays, including methods and key metrics.
  • Data examples illustrating substrate oxidation applications among various cell types.
  • Powerful applications in for cancer and immunotherapy to advance drug discoveries.


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DATE Thursday, March 05, 2020

TIME
  • 08:00 PST (Los Angeles)
  • 11:00 EST (New York)
  • 16:00 GMT (London)
Register for the webinar now >>
 
For Research Use Only. Not for use in diagnostic procedures.
PRESENTED BY
Presenter - George W. Rogers, Ph.D. George W. Rogers, Ph.D.,
Research Scientist,
Expert Bioassay Solutions,
Cell Analysis Division,
Agilent Technologies, Inc.