In this webinar, Svetlana Yatsenko of the Department of Pathology at the University of Pittsburgh will share how her team has used the 60K CGH GenetiSure microarray platform from Agilent to detect large aberrations (greater than 10 Mb in size), as well as aCGH with the “Single Cell Small Aberration Method” to detect copy number variants less than 10 Mb in size. Segmental imbalances in embryos have a significantly lower potential for implantation, leading to a diagnosis of idiopathic infertility or discovered by karyotype or microarray analysis after a miscarriage. Detection of microdeletions and duplications associated with human pathologies may improve the success rate of in vitro fertilization procedures and reduce the incidence of microdeletion syndromes.