Reactive oxygen and nitrogen species are part of normal metabolism and play prominent roles in cardiovascular (patho) physiology. Interestingly, these reactive species or their secondary products covalently modify proteins, thereby modulating enzyme...

Recent years have witnessed a growing excitement in the field of mitochondrial biology, with a dramatic increase in our appreciation of the diversity and complexity of mitochondrial function. Rather than simply acting as isolated energy-generating...

Recent discoveries have linked mitochondrial dysfunction and defects in cellular bioenergetics to the pathophysiology of many diseases including obesity, diabetes, cancer, cardiomyopathy and neurodegeneration. The introduction of Extracellular Flux...

Metabolic assays commonly lack spatial information, expressing complex metabolic information as a single output from 2D culture systems. To address these shortcomings, we leveraged the novel spheroid assay plates developed by Seahorse Bioscience for...

Diabetes increases the risk for heart failure. This increased risk is termed Diabetic Cardiomyopathy. Mitochondrial dysfunction is a characteristic of diabetic cardiomyopathy and may contribute to cardiac dysfunction. Cardiac mitochondria are...

Find upcoming Agilent Cell Analysis Technology webinars and view recordings of past webinars on key topics in cell metabolism research and bioenergetics.