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High-purity collection of semipreparative quantities at flows between 4 and 100 mL/min.
The 1260 Infinity II Preparative Fraction Collector is optimized for laboratories performing semipreparative-scale purification of milligram to low gram quantities with typical flow rates between 4 and 100 mL/min. The module features the full set of collection modes and is compatible with a wide variety of trigger sources. SBS plates and four different tube sizes with various lengths are supported.|The Preparative-Scale Fraction Collector features a compact closed-box design, requires minimal bench space, and can be seamlessly integrated into any InfinityLab Purification System. The built-in fraction delay sensor allows automated delay calibration for maximum substance recovery, and the four preconfigured capillary kits ensure minimum peak dispersion for maximum purity. Maximum capacity can be easily enhanced by clustering up to three modules.
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A preparative HPLC system with MS detector enhancing purification and maximizing productivity.
The 1260 Infinity II Preparative LC/MSD System is designed to streamline your purification process, allowing rapid purification and characterization of targets from complex mixtures, even at the smallest quantities, with high purity. |This HPLC Purification system is configurable with high-performance UV and mass spectrometry detectors (MSD) such as the Pro iQ, controlled by OpenLab CDS, along with multiple fraction collectors offering exceptional versatility. Automated sample injections increases throughput, while mass-based fraction collection ensures maximum purity and minimizes re-analysis, enhancing both the efficiency and quality of your preparative chromatography work.|The 1260 Infinity II Preparative LC/MSD System offers maximum flexibility in fraction size, focusing on your target compounds and reducing the number of collected fractions. This optimizes the fraction collection capacity and improves overall efficiency.|An HPLC preparative chromatography system with higher productivity, better purity, and smarter sample management. The right solution for modern purification.
A SFC system with broad power range up to 600 bar and 5 mL/min for extended application reach.
The 1260 Infinity III SFC System is a supercritical fluid chromatography (SFC) solution that supports pressures up to 600 bar at flow rates up to 5 mL/min. Its innovative Feed Injection technology enables reproducible injections over a wide range (0.1 to 90 µL).|The broad power range gives you an extended application reach and the use of food-grade carbon dioxide (CO2) guarantees lowest operating costs and a fast return on investment. Detection capabilities can be expanded by adding an Agilent mass spectrometer, 1260 Infinity III Evaporative Light Scattering Detector, or a SIM flame ionization detector.
Carbon dioxide (CO2) conditioning unit for InfinityLab SFC solutions.
The 1260 Infinity III SFC Control Module is a carbon dioxide conditioning unit for supercritical fluid chromatography. This module pre- and postconditions CO2 for InfinityLab SFC solutions. CO2 preconditioning provides for unmatched stability and precision of retention times, and postconditioning enables trouble-free connection to mass spectrometers.|The 1260 Infinity III SFC Control Module first liquefies gas-phase CO2 and then compresses the liquefied gas. This unique approach of precompression eliminates many of the problems caused by the thermodynamic properties of liquid-phase CO2, and enables precise composition and delivery of the mobile phase by the 1260 Infinity III SFC Binary Pump at pressures up to 600 bar.
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An affordable system with manual injection for easy entry into LC purification workflows.
The 1260 Infinity II Manual Preparative LC System is an easy-to-use, entry-level solution for LC purification with upgrade possibilities to do routine purification of milligram up to gram scale quanities of materials. This binary gradient system delivers dynamic flow rates up to 50 mL/min, equipped with a manual injection valve. The system achieves outstanding performance and reliability day-in and day-out, and is the most cost-effective way to do routine purification.
Quaternary solvent delivery at pressures up to 600 bar and flow rates up to 10 mL/min.
The 1260 Infinity III Quaternary Pump is a gradient pump that uses low-pressure mixing for UHPLC gradient formation and solvent blending from up to four solvents. This pump operates at pressures up to 600 bar and flow rates up to 10 mL/min.|The 1260 Infinity III Quaternary Pump combines proven reliability with highest flexibility in automated gradient formation and solvent blending, and is recommended for a wide range of research and routine applications as well as for method development.
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Routine HPLC/UHPLC applications, with a pressure range up to 600 bar and flow rates up to 10 mL/min.
The 1260 Infinity III LC System is a robust analytical high-performance liquid chromatography (HPLC) system that offers the widest choice of modules for analytical HPLC and entry-level UHPLC analysis. This HPLC instrument delivers the performance, reliability, and robustness you need for highest confidence in your daily HPLC results.|This analytical HPLC system delivers robust results while providing several ease-of-use features, making it the standard system for reliable routine HPLC analysis. Mix and match new modules with existing HPLC instrumentation to maximize uptime and minimize disruption. Agilent Instrument Control Framework (ICF) enables smooth control of Agilent LC instrumentation through third-party chromatography data systems.|The 1260 Infinity III LC System puts you on the fast track to efficiency, optimizing speed and resolution for HPLC analysis.
MALS Detector for determination of absolute molecular weight in GPC/SEC.
Light scattering (LS) in GPC/SEC applications is one of the few absolute techniques for the characterization of macromolecules. The 1260 Infinity II Multi-Angle Light Scattering Detector (MALS Detector) provides accurate determination of absolute molecular weight, size, radius of gyration, and conformation information of macromolecules in solution. |The 20-angle static light scattering detector allows for the simultaneous detection of the time-averaged scattering intensity at 20 different detection angles. A cylindrical flow cell design ensures robust and reliable operation for accurate results in GPC/SEC systems and applications.
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Analytical HPLC/UHPLC purification system with a pressure range up to 800 bar.
The 1260 Infinity III Prime Analytical-Scale LC Purification System is a versatile preparative high-performance liquid chromatography (HPLC) instrument. This system offers the highest functionality and operational convenience for analytical-scale HPLC purification and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min. Using this flexible HPLC/UHPLC purification system you can have the utmost confidence in purifying up to multimilligram quantities of material.|This preparative HPLC/UHPLC system has gradient and mixing performance equivalent to a 1260 Infinity III Binary LC system, provides quaternary and ternary solvent mixing, and offers functions like intelligent system emulation technology (ISET) for perfect method transfer. BlendAssist software enables automatic mobile phase blending using 1290 Infinity III Flexible Pump technology.
Wide-range, UV-spectral detection from 190 to 950 nm with 120 Hz sampling.
The 1260 Infinity III Diode Array Detector WR offers multiple wavelength and full spectral detection up to a 120 Hz sampling rate. Maximum flexibility is guaranteed with a wide wavelength range of 190 to 950 nm with dual-lamp design, as well as the choice of 15 analytical, preparative, and SFC flow cells. Even at high data rates, the 1260 Infinity III DAD WR enables precise identification, quantification, and peak purity analysis at trace levels.
Binary solvent delivery at pressures up to 600 bar and flow rates up to 5 mL/min.
The 1260 Infinity III Binary Pump uses high-pressure mixing for UHPLC gradient formation and solvent blending from one or two solvents at pressures up to 600 bar and flow rates up to 5 mL/min.|The 1260 Infinity III Binary Pump is ideally suited for a broad range of UHPLC applications using columns with conventional, superficially porous or sub-2-micron particles. This pump delivers reproducible gradients for routine HPLC or UHPLC applications with UV or MS detection where speed, resolution, and uncompromised data quality are essential.
High-sensitivity ELS detection of semi- and nonvolatiles with an evaporator range from 25 to 120 °C.
The 1260 Infinity III Evaporative Light Scattering Detector (ELSD), although targeted at analytical scale, can also be used with a flow splitter for preparative chromatography applications. It is highly recommended for compounds with little or no UV chromophore, since the detector technique evaporates the solvent and then measures the intensity of the scattered light, which is directly proportional to the sample concentration.|There is no need to make any corrections for composition: the response is independent of any optical properties. Whatever temperature and gas flow rate is selected, the detector rapidly stabilizes and can be used within minutes. There is no baseline drift to consider, baseline integration is straightforward, and reproducibility is excellent. The detector can be programmed and controlled by many available LC software packages.
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Bioanalytical HPLC/UHPLC purification system with a pressure range up to 800 bar and flow rate up to 5 mL/min.
The 1260 Infinity III Prime Bio Analytical-Scale LC Purification System is a versatile preparative high-/ultrahigh-perfomance liquid chromatography (HPLC/UHPLC) system for bioseparations. The system offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.|This biocompatible HPLC/UHPLC system is the ideal system when you need to investigate separated compounds. The 1260 Infinity II Bio-Inert Fraction Collector offers a cooling module to prevent degradation of thermally labile biomolecules.|The system consists of biocompatible material for use in biopharma (such as for critical quality attributes) and other applications using high-salt and extreme-pH conditions, ensuring biomolecule integrity and system robustness.
High-sensitivity, single-wavelength UV detection from 190 to 600 nm at 120 Hz and ±2.5 µAU/cm noise.
The 1260 Infinity III Variable Wavelength Detector enables highest productivity with fast analysis at up to 120 Hz data rates. Even more sample information can be acquired in dual-wavelength mode. Time-programmable wavelength switching provides optimum sensitivity and selectivity for your applications.| Lowest baseline noise and drift results in lowest detection limits for robust quantification of trace level components.
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Reliable analysis of biological polymers with metal-free flow path and optional advanced detectors
The 1260 Infinity II Bio-SEC System is a size exclusion chromatography (SEC) system designed to meet the challenges of analyzing biological polymers. The metal-free flow path ensures robust and reliable operation for harsh analytical conditions at high salt concentrations and extreme pH values. The 1260 Infinity II GPC/SEC Column Thermostat with optional cooling ensures sample integrity. And advanced detection methods, like multi-angle light scattering with SEC MALS detection, allow for the measurement of absolute molecular weight, size, and conformation of macromolecules in solution.|This unique combination makes the system the perfect solution for protein molar mass, purity, and aggregation analysis with advanced detection.
High-volume fraction collection for purification workflows up to 200 mL/min.
The 1260 Infinity II Preparative Valve-Based Fraction Collector is a compact, full-featured fraction collector for daily compound isolation and purification by LC. Optimized for collection of up to 11 high-volume fractions its versatile design allows operation in both routine sample purification workflows and recovery applications. The built-in fraction delay sensor allows precise and automatic calibration of the fraction collector for accurate sample collection.|This fraction collector accepts multiple detectors as trigger sources and includes all standard collection modes like time-based and peak-based. It can be used on any InfinityLab Purification System and its small dimensions occupy virtually no additonal space on the instrument. Blow-outs of nitrogen or compressed air purge the outlet lines after completed collection and help minimize carryover.
Simultaneous UV detection at up to eight wavelengths from 190 to 950 nm with 120 Hz sampling.
The diode array design of the 1260 Infinity III Multiple Wavelength Detector offers very low detector noise (less than ±7 μAU) for precise quantification of trace levels, regardless of the number of signals recorded. Over a wavelength range from 190 to 950 nm, simultaneous detection of up to eight compound-specific wavelengths for optimum selectivity is provided. High-speed UV detection with up to 120 Hz data rates keeps pace with the analysis speed of fast LC.
Easy and reliable injection of up to 20 mL of sample for routine compound purification.
The 1260 Infinity II Manual Preparative Injector is ideal for routine purification of milligram and multigram quantities at flows up to 200 mL/min. Modular sample loops in various sizes up to 20 mL volume allow application in many different purification workflows.|This injector is the entry into purification workflows, easy to use, and highly reliable. Attaching to the Agilent 1260 Infinity II Preparative Column Organizer, it does not add to the total instrument bench space. This affordable, hand-operated injection valve fits to any InfinityLab Purification System.
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GPC/SEC system for routine polymer analysis with high sample throughput and accurate temperature control.
The 1260 Infinity II GPC/SEC System is designed to meet the challenges faced by today’s polymer analysis. This versatile size exclusion chromatography (SEC) and gel permeation chromatography (GPC) system provides accuracy and high performance.|The system includes a 1260 Infinity II Vialsampler for higher unattended sample throughput and a 1260 Infinity II GPC/SEC Column Thermostat for accurate temperature control and high column capacity for in-row column connection. The 1260 Infinity II Isocratic Pump achieves extra flow precision, and the 1260 Infinity II Refractive Index Detector gives precise results from your GPC/SEC instrument. Additional GPC/SEC special detection capabilities like multi-angle light scattering (MALS) detectors or viscometry can be added for flexibly.
High capacity with LC-like injection precision and reproducibility for SFC and SFC/MS applications.
The 1260 Infinity III SFC Multisampler is a high-capacity autosampler for supercritical fluid chromatography, bringing LC-like injection precision and reproducibility to SFC. The wide injection range supports flexible injection volumes from 0.1 to 90 µL without changing sample loops.|The 1260 Infinity III SFC Multisampler is compatible with 2 mL vials and well plates for fast, high-throughput (up to 6,144 samples) SFC and SFC/MS applications. Innovative Feed Injection technology pressurizes the sample prior to injection into the carbon dioxide (CO2) stream for utmost injection precision and reproducibility.