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1260 Infinity III LC System

Routine HPLC/UHPLC applications, with a pressure range up to 600 bar and flow rates up to 10 mL/min.

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The 1260 Infinity III LC System is a robust analytical high-performance liquid chromatography (HPLC) system that offers the widest choice of modules for analytical HPLC and entry-level UHPLC analysis. This HPLC instrument delivers the performance, reliability, and robustness you need for highest confidence in your daily HPLC results.|This analytical HPLC system delivers robust results while providing several ease-of-use features, making it the standard system for reliable routine HPLC analysis. Mix and match new modules with existing HPLC instrumentation to maximize uptime and minimize disruption. Agilent Instrument Control Framework (ICF) enables smooth control of Agilent LC instrumentation through third-party chromatography data systems.|The 1260 Infinity III LC System puts you on the fast track to efficiency, optimizing speed and resolution for HPLC analysis.

1260 Infinity II Multi-Angle Light Scattering Detector

MALS Detector for determination of absolute molecular weight in GPC/SEC.

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Light scattering (LS) in GPC/SEC applications is one of the few absolute techniques for the characterization of macromolecules. The 1260 Infinity II Multi-Angle Light Scattering Detector (MALS Detector) provides accurate determination of absolute molecular weight, size, radius of gyration, and conformation information of macromolecules in solution. |The 20-angle static light scattering detector allows for the simultaneous detection of the time-averaged scattering intensity at 20 different detection angles. A cylindrical flow cell design ensures robust and reliable operation for accurate results in GPC/SEC systems and applications.

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1260 Infinity III Method Development System

Screen more than 100 sets of separation conditions with up to 15 mobile phases and 4 columns.

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The 1260 Infinity III Method Development System provides robust and reliable technology for everyday automated HPLC method development challenges. An increased performance and flexibility are provided by the 1260 Infinity III Prime LC instrumentation. Make use of this method development instrument to screen more than 100 different sets of LC separation conditions without the need for manual interaction. Automatically access 15 different mobile phases and 4 columns with 2 independent temperature zones.|With the 1260 Infinity III Flexible pump, the use of intelligent system emulation technology (ISET) is enabled and allows emulation of other selected LC systems for straightforward and seamless transfer of your optimized methods.

1260 Infinity III Multisampler

Injection from vials and micoplates of up to 6,144 samples at up to 800 bar.

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The 1260 Infinity III Multisampler is a multipurpose autosampler that handles vials and microplates. Injecting at pressures up to 600 or 800 bar, the Multisampler is a compact module with a capacity of up to 6,144 samples, all within the footprint of an Agilent LC stack.|The 1260 Infinity III Multisampler is optimized for highest flexibility. The unique dual-needle design enables cycle times to be reduced by overlapping sample runs and injection cycles. The multiwash capability reduces carryover to less than 9 ppm.

1260 Infinity III Variable Wavelength Detector

High-sensitivity, single-wavelength UV detection from 190 to 600 nm at 120 Hz and ±2.5 µAU/cm noise.

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The 1260 Infinity III Variable Wavelength Detector enables highest productivity with fast analysis at up to 120 Hz data rates. Even more sample information can be acquired in dual-wavelength mode. Time-programmable wavelength switching provides optimum sensitivity and selectivity for your applications.| Lowest baseline noise and drift results in lowest detection limits for robust quantification of trace level components.

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1260 Infinity III Prime LC System

HPLC/UHPLC quaternary solvent mixing with pressure range up to 800 bar and flow rates up to 5 mL/min.

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The 1260 Infinity III Prime LC System is an analytical ultrahigh-performance liquid chromatography instrument. It operates at high pressures and can handle flow rates up to 5 mL/min for using UHPLC columns packed with sub-2 μm particles. This HPLC/UHPLC system gives you the utmost confidence in your HPLC results and is a perfect front end for your LC/MS system. A broad range of detection options is available on this quaternary UHPLC system for routine HPLC analysis. |As a quaternary system, this flexible HPLC/UHPLC instrument combines high performance and high flexibility. It has gradient formation and mixing performance equivalent to a binary-like system. It provides quaternary and ternary solvent mixing for excellent retention time reproducibility, accuracy, and precision. |This system also offers technology functions, such as Agilent Intelligent System Emulation Technology (ISET) and Blend Assist. With ISET, you can seamlessly transfer methods from Agilent or non-Agilent HPLC/UHPLC systems, eliminating the need for time-consuming method redevelopment. Blend Assist simplifies UHPLC system workflows and accelerates method development by automating mobile phase blending.

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1260 Infinity III Prime Bio Analytical-Scale LC Purification System

Bioanalytical HPLC/UHPLC purification system with a pressure range up to 800 bar and flow rate up to 5 mL/min.

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The 1260 Infinity III Prime Bio Analytical-Scale LC Purification System is a versatile preparative high-/ultrahigh-perfomance liquid chromatography (HPLC/UHPLC) system for bioseparations. The system offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.|This biocompatible HPLC/UHPLC system is the ideal system when you need to investigate separated compounds. The 1260 Infinity II Bio-Inert Fraction Collector offers a cooling module to prevent degradation of thermally labile biomolecules.|The system consists of biocompatible material for use in biopharma (such as for critical quality attributes) and other applications using high-salt and extreme-pH conditions, ensuring biomolecule integrity and system robustness.

1260 Infinity III SFC Control Module

Carbon dioxide (CO₂) conditioning unit for InfinityLab SFC solutions.

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The 1260 Infinity III SFC Control Module is a carbon dioxide conditioning unit for supercritical fluid chromatography. This module pre- and postconditions CO₂ for InfinityLab SFC solutions. CO₂ preconditioning provides for unmatched stability and precision of retention times, and postconditioning enables trouble-free connection to mass spectrometers.|The 1260 Infinity III SFC Control Module first liquefies gas-phase CO₂ and then compresses the liquefied gas. This unique approach of precompression eliminates many of the problems caused by the thermodynamic properties of liquid-phase CO₂, and enables precise composition and delivery of the mobile phase by the 1260 Infinity III SFC Binary Pump at pressures up to 600 bar.

1260 Infinity III Multiple Wavelength Detector

Simultaneous UV detection at up to eight wavelengths from 190 to 950 nm with 120 Hz sampling.

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The diode array design of the 1260 Infinity III Multiple Wavelength Detector offers very low detector noise (less than ±7 μAU) for precise quantification of trace levels, regardless of the number of signals recorded. Over a wavelength range from 190 to 950 nm, simultaneous detection of up to eight compound-specific wavelengths for optimum selectivity is provided. High-speed UV detection with up to 120 Hz data rates keeps pace with the analysis speed of fast LC.

1260 Infinity II Degasser

High-capacity degassing at flow rates up to 10 mL/min for GPC/SEC and other high-flow applications.

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The 1260 Infinity II Degasser is suitable for analytical applications with flow rates up to 10 mL/min and up to four solvents. It is highly recommended for GPC/SEC applications using refractive index detection. It reduces baseline noise and quenching effects due to high degassing capacity.|Agilent provides a number of high quality degassing solutions that deliver excellent performance in any application. Agilent integrated degassing units are integral parts of Agilent LC modules and systems and are not available individually.

1260 Infinity III Manual Injector

Compact, affordable manual injection of samples at up to 600 bar operating pressure.

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The 1260 Infinity III Manual Injector is an HPLC valve for manual injection of samples at pressures up to 600 bar. It is supplied with a baseplate, which is dimensioned to match the footprint of all 1260 Infinity modules. The 1260 Infinity III Manual Injector is a compact, affordable solution for sample injection.

1260 Infinity II Preparative Column Organizer

Secure mounting of analytical and preparative columns for purification workflows.

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The 1260 Infinity II Preparative Column Organizer is a support module for purification workflows. It provides convenient and stable mounting of a manual injector and easily organizes both analytical and preparative columns from 4.6 to 50 mm inner diameter.|This compact module can be easily attached to any InfinityLab LC Purification System, saving valuable bench space in your laboratory. It provides a leak sensor for additional safety during operation and is flexibly designed to support any purification workflow with column lengths from 50 to 250 mm.

1260 Infinity II Preparative Autosampler

Automated sample handling from vials for routine preparative workflows.

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The 1260 Infinity II Preparative Autosampler is designed for automated sample handling in routine purification applications. This flow-through vialsampler supports preparative flow rates of 200 mL/min and 400 bar pressure. Increase your daily throughput of purified sample by injecting up to 132 preparative samples with a maximum of 5 mL volume.|The 1260 Infinity II Preparative Autosampler is easy to use, reliable, and can be integrated into any InfinityLab Purification System.

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1260 Infinity II Preparative LC/MSD System

A preparative HPLC system with MS detector enhancing purification and maximizing productivity.

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The 1260 Infinity II Preparative LC/MSD System is designed to streamline your purification process, allowing rapid purification and characterization of targets from complex mixtures, even at the smallest quantities, with high purity. |This HPLC Purification system is configurable with high-performance UV and mass spectrometry detectors (MSD) such as the Pro iQ, controlled by OpenLab CDS, along with multiple fraction collectors offering exceptional versatility. Automated sample injections increases throughput, while mass-based fraction collection ensures maximum purity and minimizes re-analysis, enhancing both the efficiency and quality of your preparative chromatography work.|The 1260 Infinity II Preparative LC/MSD System offers maximum flexibility in fraction size, focusing on your target compounds and reducing the number of collected fractions. This optimizes the fraction collection capacity and improves overall efficiency.|An HPLC preparative chromatography system with higher productivity, better purity, and smarter sample management. The right solution for modern purification.

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1260 Infinity II Multidetector GPC/SEC System

Characterizes polymers accurately and efficiently using RID, light scattering, or viscometry.

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With the 1260 Infinity II Multidetector GPC/SEC System, you can select from any combination of detection by refractive index, light scattering, and viscometry. This GPC/SEC system with triple detection delivers accurate, absolute molecular weights and sizes, and can be used to analyze a wide range of polymers, regardless of molecular weight range or solvent. Each detector has independent temperature control to ensure that high levels of precision and reproducibility can easily be achieved from one day to the next.

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1260 Infinity II Preparative LC System

Ideal workhorse system for laboratory-scale LC purification.

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The 1260 Infinity II Preparative LC System is a reliable and robust UV based HPLC purification system. This UV HPLC instrument maximizes purity with fully automated sample injections that increases your daily production, and minimizes reanalysis time through mass-based purification.|The 1260 Infinity II Preparative LC System is an easy-to-use workhorse for automated sample injection when gradient elution is required. The binary gradient pump delivers flow rates up to 50 mL/min for purification up to 30.0 mm id columns. This preparative HPLC system is tailor-made for routine, laboratory-scale purification when milligrams to grams of starting material are available and can be upgraded to further enhance the system.

1260 Infinity III Fluorescence Detector Spectra

High-sensitivity, multisignal data and spectra in a single run at up to 148 Hz.

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The 1260 Infinity III Fluorescence Detector Spectra is a sensitive HPLC fluorescence detector that simultaneously provides quantitative data and fluorescence spectra from a single run, enabling rapid method optimization for HPLC FLD Detector Spectra experiments.|Use the online spectral information for rapid method optimization and verification of separation quality. High-speed detection features up to 148 Hz data rates for very narrow peaks. This detector can be used with any Agilent InfinityLab LC Series system or other LC instrument.

1260 Infinity III SFC Binary Pump

600 bar and 5 mL/min power range for extended SFC and SFC/MS application reach.

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The 1260 Infinity III SFC Binary Pump is a supercritical fluid chromatography (SFC) pump that supports high-pressure gradient formation and precise mobile phase delivery up to 5 mL/min and 600 bar. It can be used with a broad range of chiral and achiral columns, and ideal for fast, high-throughput SFC and SFC/MS applications.|The 1260 Infinity III SFC Binary Pump is equipped with special pistons and seals for utmost robustness under SFC conditions. Carbon dioxide (CO₂) is delivered through channel A while organic modifier can be added through channel B for either isocratic or gradient elution. Channel B is fitted with a purge valve to facilitate rapid change of organic modifier.

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1260 Infinity II High-Temperature GPC System

HT-GPC System for reproducible characterization of any polymer at high temperatures up to 220 °C.

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The 1260 Infinity II High-Temperature GPC System (HT-GPC) can provide information about all of today’s engineering polymers such as polyolefins, which are one of the most popular polymers with numerous applications. This level of detail helps with development and to predict how a given batch will process and perform in the final product.|Traditionally challenging materials such as polyethylene and polyamides can be analyzed routinely regardless of detection technique. High-temperature light scattering, viscometry, and concentration detectors (RID and HTELSD) all deliver a wealth of information, whatever your polymer of interest.

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1260 Infinity III Bio-Inert Analytical-Scale LC Purification System

Bio-inert analytical HPLC purification system with corrosion-resistant flow path to protect biomolecules

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The 1260 Infinity III Bio-Inert Analytical-Scale LC Purification System is a dedicated solution for purifying large biomolecules in biological samples, including monoclonal antibodies and proteins. |This bio analytical preparative HPLC system comes with metal-free components in the sample flow path. The absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.|The power range of this bio-inert HPLC purification system expands from low pressure, for traditional biopurification columns, up to high pressure, for sub-2-micron analytical biocolumns. The 1260 Infinity III Bio-Inert Fraction Collector offers a cooling module to prevent degradation of thermally labile biomolecules. Buffer Advisor software facilitates faster pH scouting and easy buffer/solvent preparation for ion-exchange chromatography (IEX).