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Alpha assays are trademark proximity assay platforms from PerkinElmer, Inc. The bead-based methods requires powerful excitation to produce a cascade of acceptor bead emission wavelengths.
Alpha assays are trademark proximity assay platforms from PerkinElmer, Inc. The bead-based methods requires powerful excitation to produce a cascade of acceptor bead emission wavelengths.
Endoplasmic reticulum (ER) mediated cell stress and the unfolded protein response (UPR) serve as major stress pathways in eukaryotic cells. ER stress and the UPR can be triggered by various cellular perturbations, including misregulation of ER Ca2+,...
The Enzyme-Linked ImmunoSpot (ELISpot) assay is a flexible and sensitive method for investigating the frequency of cytokine-secreting cells within a population. In virology and vaccine research, this assay provides a useful format for evaluating the...
Accurate cell counting is a critical step across a spectrum of cell biology applications. Direct cell counting uses methods that identify and enumerate individual cells, as opposed to indirect methods that estimate population sizes using...
Histology and tissue imaging is typically performed on fixed tissue samples using time-intensive manual upright microscopes equipped with oculars. Sample variety and applications span diverse biology and research areas.
Activated immune cells undergo rapid expansion in response to foreign antigens or disease exposure. T cells cluster together to transmit essential information through a series of interactions and coordinate to fight invading pathogens. Monitoring...
Cytation C10 brings you more efficient, gentle detection of dim fluorescent signals, improved image quality, and compatibility.
Agilent offers a comprehensive portfolio of integrated solutions for reliable results from discovery through QC to empower researchers with the confidence to achieve breakthroughs.
The plaque assay is a well-established method for measuring virus concentration as it relates to infectious dose. The assay relies on determining the number of plaque-forming units (PFU) created in a monolayer of virus-infected cells.
Cell cycle progression is a tightly regulated process that involves the duplication of nuclear DNA content prior to cell division. The control mechanisms that regulate this process are often disrupted in tumor cells and serve as viable targets for...
The advent of permeable supports has provided a simple in vitro approach to measure chemoattractant-induced cell migration and invasion. The addition of a fluorescence blocking membrane enables detection of migrated labeled cells within the well....
Host protein receptor expression is the ultimate factor that determines if a host cell is permissible to viral entry and infection. In viral research, it is essential to determine which cell types, primary or immortalized, are permissible to viral...
Cell proliferation is a process where cells grow and divide in order to replenish cells that have died or to expand a population.
The power of the well-known Seahorse XF technology from Agilent Technologies lies in its ability to simultaneously and kinetically measure mitochondrial respiration and glycolysis – two major energy pathways – in live cells. By doing so, researchers...
The Victorian Centre for Functional Genomics (VCFG) supports and propels research efforts across Australia. Located at the Peter MacCallum Cancer Centre in Melbourne, Victoria, this core facility’s ”researcher driven, staff assisted” ethos is...
Small molecule-induced protein degradation is a promising modality in novel, highly targeted cancer therapy development and beyond. Within this realm, Monte Rosa Therapeutics in Boston, Massachusetts, has particular expertise working with small...
DiscoveryBioMed, Inc., supplies products and services to help the drug discovery community improve attrition rates and pinpoint compounds that are high-value clinical candidates. Since its founding in 2007 by physiologist Dr. Erik Schwiebert, this...
Differentiating a stem cell into a neuron or glial cell is typically a time-consuming bottleneck in human neurological dysfunction research. On top of this, precisely controlling the purity of sub-types in a mixed neuron population can be a complex...
Explore a comprehensive portfolio of sample-to-data cell therapeutic development solutions that work seamlessly together to provide reliable results. Find application notes, webinars, and more.