Many viruses do not form traditional plaques, and there may not be tools readily available to determine viral foci by immunolabeling or fluorescent reporters often used for viral titration. In these cases, viral infection can be detected using...

Macrophages and other phagocytes are specialized cells that consume and digest foreign matter or aberrant cells through phagocytosis. pH-sensitive bioparticles or probes, including pHrodo-labeled zymosan bioparticles, are a useful tool to study...

The Enzyme-Linked ImmunoSpot (ELISpot) assay is a flexible and sensitive method for investigating the frequency of cytokine-secreting cells within a population. In virology and vaccine research, this assay provides a useful format for evaluating the...

Robust cell-based research relies on the consistent maintenance and evaluation of samples and reproducible assay setup. This can be particularly hard to achieve given the complex behavior of cell biology and the variable nature of many cell culture...

The advent of permeable supports has provided a simple in vitro approach to measure chemoattractant-induced cell migration and invasion. The addition of a fluorescence blocking membrane enables detection of migrated labeled cells within the well....

Life science laboratories around the globe have their own unique requirements for instrumentation. The Agilent BioTek high quality microplate readers offer excellent sensitivity, fast speeds, low maintenance costs, and simple, yet amazingly powerful...