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Epidermal growth factor receptor (EGFR) is a transmembrane receptor encoded by the human HER1 gene. EGFR is a member of the EGF/erbB receptor family of related growth factor receptors, which include HER2/erbB2 or neu, HER3/erbB3, and HER4/erbB4. The...
Levels of steroid hormone receptors (estrogen and progesterone receptors) can aid in predicting which women are likely to benefit from hormone treatment. Treatment guidelines recommend measurement of steroid hormone receptors status in the...
Overexpression of HER2 protein has been described in some cancer types. HER2 protein is a target for HER2-specific treatments. HercepTest™ pharmDx kits are available for immunohistochemical determination of HER2 protein overexpression using...
The human HER2 gene with the generic name ERBB2 (also known as NEU) encodes the HER2 protein or p185HER2. The HER2 protein is a membrane receptor tyrosine kinase with homology to the epidermal growth factor receptor (EGFR). The HER2 gene is a normal...
Cytotoxic T cells work to detect and eliminate infected cells and tumor cells from the body. To limit damage to surrounding tissue, normal cells differentiate themselves by expressing a protein signal called PD-L1 (programmed death ligand 1). This...
Cytotoxic T cells work to detect and eliminate infected cells and tumor cells from the body. To limit damage to surrounding tissue, normal cells differentiate themselves by expressing a protein signal called PD-L1 (programmed death ligand 1). This...
HercepTest for the Dako Autostainer, Kit system, Immunohistochemistry pharmDx, 50 tests
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Regulatory Status:
IVD
HER2 IQFISH pharmDx, Kit system, In Situ Hybridization pharmDx, 20 tests
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Regulatory Status:
IVD
EGFR pharmDx Kit for the Dako Autostainer, Ready-to-use, Immunohistochemistry pharmDx, 50 tests
EGFR pharmDx Kit is a qualitative immunohistochemical kit system that includes all reagents necessary to identify expression of epidermal growth factor receptor (EGFR) protein on the surface of normal and neoplastic cells. EGFR protein is also...
PD-L1 IHC 28-8 pharmDx is a qualitative IHC assay intended for use in the detection of PD-L1 protein in FFPE tissues using EnVision FLEX visualization system on Autostainer Link 48.
The kit includes reagents required for the immunohistochemical staining (except wash buffer), control slides representing different expression levels of PD-L1 protein, and detailed instructions. The kit has been tailored especially for use on Autostainer Link 48 instruments. The materials provided are sufficient for 50 tests (50 slides incubated with monoclonal rabbit antibody to PD-L1 and 50 slides incubated with the corresponding Negative Control Reagent, 100 slides in total).|PD-L1 IHC 28-8 pharmDx is subject to an exclusive trademark license to Agilent Technologies, Inc. OPDIVO® is a trademark owned by Bristol-Myers Squibb.|Read more about <a href=/en/product/pharmdx/pd-l1-ihc-28-8-overview >PD-L1 IHC 28-8 pharmDx </a >.|Interpretation training is now available for PD-L1 IHC 28-8 pharmDx. To learn more, visit PD-L1 IHC 28-8 pharmDx eLearning.
EGFR pharmDx Kit is a qualitative immunohistochemical kit system that includes all reagents necessary to identify expression of epidermal growth factor receptor (EGFR) protein on the surface of normal and neoplastic cells. EGFR protein is also...
PD-L1 Control Slides are intended for use as optional quality control material when stained with PD-L1 IHC 22C3 pharmDx, Code GE006.
ER/PR pharmDx Kits are semi-quantitative immunohistochemical kit systems to identify estrogen receptor (ER) α protein and progesterone receptor (PR) protein expression in normal and neoplastic tissues. The assay specifically detects the ER...
HercepTest is a semi-quantitative immunohistochemical assay for determination of HER2 protein (c-erbB-2 oncoprotein) overexpression in breast cancer tissues routinely processed for histological evaluation and formalin-fixed, paraffin-embedded cancer...
ER/PR pharmDx Kits are semi-quantitative immunohistochemical kit systems to identify estrogen receptor (ER) α protein and progesterone receptor (PR) protein expression in normal and neoplastic tissues. The assay specifically detects the ER...
HER2 IQFISH pharmDx is a direct fluorescence in situ hybridization (FISH) assay based on Dako's new fast IQISH hybridization buffer chemistry. The IQISH hybridization buffer is non-toxic and allows genomic DNA probe hybridization to be...
PD-L1 IHC 22C3 pharmDx is a qualitative IHC assay intended for use in the detection of PD-L1 protein in FFPE tissues using EnVision FLEX visualization system on Autostainer Link 48.
for indications and PD-L1 expression levels.|For details on staining interpretation, refer to section 13 of the Instructions for Use and indication-specific PD-L1 IHC 22C3 pharmDx Interpretation Manuals.|PD-L1 IHC 22C3 pharmDx
The kit includes reagents required for the immunohistochemical staining (except wash buffer), control slides representing positive and negative PD-L1 protein expression, and detailed instructions. The kit has been tailored especially for use on Autostainer Link 48 instruments. The materials provided are sufficient for 50 tests (50 slides incubated with monoclonal mouse antibody to PD-L1 and 50 slides incubated with the corresponding negative control reagent, 100 slides in total).|Read more about PD-L1 IHC 22C3 pharmDx.|For countries outside of the United States, see the local KEYTRUDA product label for approved indications and expression cutoff values to guide therapy.|KEYTRUDA® is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.|LIBTAYO is a registered trademark of Regeneron Pharmaceuticals, Inc.