Measure With Confidence Both Size And Concentration Of DNA Fragments
When samples have insufficient nuclear DNA present for effective analysis (due to damage, degradation or limited sample availability) mitochondrial DNA (mt-DNA) testing can be used to determine the maternal lineage of a DNA sample. The solution is often used to identify remains of service personnel or disaster victims, as well as to analyze historical samples.
Accurately measuring both the size and concentration of DNA fragments prior to analysis is a key challenge in this area. The Agilent 2100 Bioanalyzer and DNA 500 LabChip carry such analyses quickly and effectively to the required precision for further mt-DNA classification. The systems also enable the optimization of PCR analyses through rapid quantitative analysis of both mt-DNA amplification products and PCR artifacts.