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SureSelectXT HS Workflow

Many needs. One sure solution.

SureSelectXT HS Workflow

The SureSelectXT HS product family is Agilent's state-of-the-art library prep and target enrichment solution. It offers a fast, streamlined and highly sensitive workflow. You can use small amounts of FFPE DNA as input and detect allele frequency down to 1% or lower, making it a great tool for cancer research. With the advanced new features, it could satisfy most, if not all, of your needs for NGS sample preparation.

The SureSelectXT HS product family can be used with both catalog and custom NGS panels. Custom panels can be designed in SureDesign, a free web-based design portal that makes panel design fast and easy.

Workflow Key Features (Mouse over feature for details.) SureSelect XT HS Workflow Flexible DNA shearing workflows Enzymatic or mechanical shearing Unique dual indexing Unique dual sample indexing to address index hopping (cannot be combined with Molecular barcode) Automation A single vendor solution for both reagents and automation One-day workflow Fast 90-min hybridization to enable a one-day workflow Molecular barcode Molecular barcode to detect allele frequency down to 1% or lower As low as 10 ng DNA input Input can go as low as 10 ng depending on the DNA quality FFPE optimized Optimized for FFPE samples with highly degraded DNA

Hear what customers are saying

"One of the best kits we have tested out of the box."

- Dr. Johnathan Keats, Director of Bioinformatics & Assistant Professor, Translational Genomics Research Institute

"This customizable target enrichment technology, with integrated molecular barcode error correction, enables us to detect ultra-low mutation frequencies in very small DNA quantities. This makes it ideal for the detection and tracking of clonal and subclonal variants in liquid biopsies."

- Dr. Marco Gerlinger of the Institute of Cancer Research and the Royale Marsden Hospital in London.

Recorded Webinars

Recorded Webinar

Hear Dr. Gerlinger speak about this liquid biopsy application.

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Recorded Webinar

Hear Dr. Singh compare
SureSelectXT HS to six different library prep kits.

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Literature Downloads

Ultra-sensitive Cancer Liquid Biopsy Analysis with the Agilent SureSelectXT HS Target Enrichment Workflow

Ultra-sensitive Cancer Liquid Biopsy Analysis with the Agilent
SureSelectXT HS Target Enrichment Workflow

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Comparisons among Six Different Library Preparation Kits using FFPE Samples for Exome Enrichment Applications

Comparisons among Six Different Library Preparation Kits using FFPE Samples for Exome Enrichment Applications

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Learn more about the new SureSelect XT HS and XT Low Input Enzymatic Fragmentation Kit

Learn more

For more information about the SureSelectXT HS and SureSelectXT Low Input Reagents Kits,
visit the product pages.

For Research Use Only. Not for use in diagnostic procedures.