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Agilent 5977B GC/MSD - The Source of New Possibilities

The Source of New Possibilities

Agilent 5977B GC/MSD system

Bring the power of the Agilent single quadrupole GC/MSD system to work for your lab

At Agilent, we innovate to maximize laboratory operations and business success. This process is reflected in the Agilent 5977B GC/MSD system.

Built to handle analytical challenges for industries such as environmental, chemical, petrochemical, food, forensic, pharmaceutical, and material testing, the 5977B GC/MSD delivers:

  • A 10-fold increase in single-quadrupole capabilities. The 5977B has detection limits as low as <1.5 fg IDL. And we guarantee it at installation checkout.
  • Lower operational costs. Higher sensitivity allows you to reduce the volume of sample you need to collect and process by up to 90%.
  • More uninterrupted lab productivity. Highly sensitive ion sources and proven robustness ensure better efficiency and less maintenance.
  • Minimal environmental impact. Less solvent for sample preparation means less hazardous waste to dispose of.
  • Support from Agilent CrossLab service experts to keep your system running at peak performance.

First in GC/MS innovation

For more than 50 years, Agilent has been leading the way for technologies like these:

  • Triple-channel EM with Triple Axis Detector (doubly off-axis) for eliminating neutral noise
  • JetClean for ion source maintenance
  • Capillary flow technology (CFT)
  • The first commercially integrated midpoint, intracolumn backflush

The Agilent 5977B GC/MSD was named “Most Popular Instrument” at the 2017 Conference of China Scientific Instruments. This award is the highest industry recognition in China.

On-demand webinar

High Efficiency Source in GC/MS: Using Sensitivity to Enhance Productivity

You’ll learn how to:

  • Maintain limits of detection while reducing sample size.
  • Identify trace-level environmental contaminants using modern GC/MSD.
  • Apply automation to your water and environmental sample analysis.
  • Automate liquid-liquid extraction, and choose the right extraction style.
Watch now


Jonathan Dunscombe
Applications Specialist, Anatune Ltd

Lakshmi Krishnan
GC/MS Single Quadrupole Product Manager, Agilent Technologies, Inc.

Agilent 5977B brochure

The Source of New Possibilities

Learn how the 5977B GC/MSD can help you improve sample throughput, analytical performance, and business outcomes.

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Application brief

EPA 8270 Re-optimized for Widest Calibration Range on the 5977 Inert Plus GC/MSD

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Agilent 5977B GC/MSD citation index

Read articles from peer-reviewed journals on how labs boost their productivity and improve sample throughput, analytical performance, and business outcomes using the Agilent 5977B GC/MSD.

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Turn Cleaning Time into Productive Time

Agilent JetClean self-cleaning ion source for GC/MS

See how JetClean technology can increase your productivity, data consistency, and convenience—and save you money. The e-book includes a built-in cost calculator to help you put a monetary value on the benefits of self-cleaning.

Free e-book

Cost calculator is included

Plug in the numbers that are relevant to your lab and see the impact JetClean can have on your operation.

Complete solutions to boost lab productivity

Agilent MassHunter software

Enables powerful data collection, processing, and reporting tools allowing you to breeze through application specific workflows with comprehensive support of GC and GC/MS technology.

  • Use one software for all Agilent GC and GC/MSD instruments including single quadrupole, tandem quadrupole and Q-TOF
  • Analyze complex samples including environmental or food matrices with compound-based analysis and reporting workflows using MassHunter Quantitative Analysis with Quant-My-Way customization.
  • Simplify data analysis with powerful application-specific software such as personal compounds, databases, and libraries.
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Agilent inert flowpath solutions

As available sample becomes increasingly small, active, and complex, you cannot afford interferences caused by flowpath activity. Agilent inert flowpath solutions ensure a reliably inert flowpath. And that means higher sensitivity, accuracy, and reproducibility.

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JetClean self-cleaning ion source

The patented Agilent JetClean self-cleaning ion source greatly reduces—or even eliminates—the need for source cleaning. A carefully controlled flow of hydrogen ensures that the ion source is kept free from contamination, protecting the integrity of your results.

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Go green, go dry: Agilent IDP-3 oil-free vacuum pump

Agilent IDP oil-free pumps really are oil free, and that makes all the difference. They deliver lower ownership costs, quiet operation, and minimal downtime—plus less hazardous waste in our environment.

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A choice of ion source configurations


  • Performance similar to previous Agilent MSD instruments—at a budget-friendly price
  • Designed for sample-dependent applications

Inert Plus EI MSD

  • High sensitivity for active compounds that interact with noninert surfaces
  • Optimum efficiency for routine labs

High-efficiency source (HES) MSD

  • Unparalleled sensitivity for ultratrace-level applications
  • Ideal for high-throughput labs
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See how the 5977B can transform your lab

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