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QuikChange Lightning

QuikChange Lightning: the New Gold Standard for Site-Directed Mutagenesis

Since 1996, the QuikChange method has provided researchers with an easy 3-step process to create point mutations, deletions, and insertions in a variety of plasmid types. The latest additions to this product line, the QuikChange Lightning Site-Directed Mutagenesis Kit and QuikChange Lighting Multi Site-Directed Mutagenesis Kit, have an accelerated protocol (one hour for a single site; three hours for multiple sites) that maintains the same mutation efficiency, reliability, and accuracy established by the original QuikChange and QuikChange II kits.

Key features:
  • Efficient mutagenesis
    >85% for 1 site, >55% for 3 sites
  • Non-PCR method
    Eliminates unwanted second site-errors
  • Fast high-fidelity polymerase
    Short extension times—30 sec/Kb
  • Quick parental template elimination
    5 minute DpnI digestion
  • Flexible (single site)
    Works on template sizes: 4-14 Kb
Watch eSeminar
Learn about the benefits of using QuikChange Lightning from one of its creates, Dr.Holly Hogrefe.
Download Information
Download data sheets for
QuikChange Lightning Single Site
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QuikChange Lightning Multi-site
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current QuikChange kit.
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Store Type: Genomics