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Interface Cone Comparison Study

Are You Sure About the Quality and Performance of Your ICP-MS Cones?

We put them to the test in our latest
cone comparison

Only Agilent cones meet our strict manufacturing specifications, confirmed by our 100% quality inspection, and protected by our custom packaging. The result: you get the sensitivity and stability that you expect from your single-quadrupole and triple-quadrupole ICP-MS systems.

Insights from the report

In our study, we compared Agilent interface cones with those from different suppliers, focusing on properties critical to ICP-MS performance. Here’s what we found:

Genuine Agilent cones deliver superior sensitivity across the mass range

Third-party cones showed lower sensitivity as received, and after following our conditioning guidelines.

Sensitivity out of the box for new cone pairs

Agilent and third-party cones show a significant difference in stability

Agilent ICP-MS cones ensure robust conditions, improving signal stability and matrix tolerance.

Third-party cones can compromise short- and long-term stability—leading to sample reruns and lost productivity.

Long-term stability for non-Agilent cones (Competitor G)

All cones are not created equal

We uncovered differences in weight between Agilent cones and third-party manufactured cones. This implies that
third-party cones deviate from the Agilent design, which can negatively impact performance.

Average weight of sampling cones as received

Want to see all the comparative data?

Download our technical overview

Already convinced?

Troubleshooting and
Maintenance of
ICP-MS Systems
Part 4: Interface Region

Learn simple cone cleaning steps that can extend cone life, eliminate drift, and minimize costly downtime.

Optimize ICP-MS performance and maximize cone life

On-demand webinar


How to master the art of cone performance

We’ll guide you through selecting the right cones for your instrument and applications, and explore the best practices for cone maintenance.

Extra value bundle


Our LED measuring magnifier is bundled with every Agilent cone care package

This field-proven tool makes cone inspection simpler and more reliable. Agilent’s cone care packages give you all the supplies needed to replace and maintain your interface cones.

Supplies resource


Agilent spectroscopy supplies catalog

More than 200 pages of essential supplies, ordering information, and valuable tips.

To access our cone comparison technical overview—or to
find out more—complete this form.