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SureFISH ROS1 BA P5

SureFISH ROS1 BA P5

SureFISH ROS1 BA P5 is recommended for the detection of rearrangements involving the ROS1 gene by fluorescence in situ hybridization (FISH). The probe can be used on formalin-fixed, paraffin-embedded tissue sections.

SureFISH ROS1 BA P5 consists of two child probes (3’ and 5’ probes), each labeled in a different color (Cy3 and FITC). The child probes are designed to hybridize on opposite sides of the translocation break point for the ROS1 gene. Following a translocation, the signals are “broken apart” and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).

Child Probe 5' GR, Chr6

Start 117747013, Stop 118899513

Child Probe 3' RD, Chr6

Start 117320499, Stop 117609677

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