SureFISH ROS1 BA P200 is recommended for the detection of rearrangements involving the ROS1
gene by fluorescence in situ hybridization (FISH). The probe can be used on formalin-fixed, paraffin-embedded tissue sections.
SureFISH ROS1 BA P200 consists of two child probes (3 and 5 probes), each labeled in a different color (Cy3 and FITC). The child probes are designed to hybridize on opposite sides of the translocation break point for the ROS1
gene. Following a translocation, the signals are broken apart and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).
Child Probe 5' GR, Chr6
Start 117747013, Stop 118899513
Child Probe 3' RD, Chr6
Start 117320499, Stop 117609677