SureFISH RET BA P5 is recommended for the detection of rearrangements involving the RET
gene by fluorescence in situ hybridization (FISH). The probe can be used on formalin-fixed, paraffin-embedded tissue sections.
SureFISH RET BA P5 consists of two child probes (3 and 5 probes), each labeled in a different color (Cy3 and FITC). The child probes are designed to hybridize on opposite sides of the translocation break point for the RET
gene. Following a translocation, the signals are broken apart and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).
Child Probe 5' GR, Chr10
Start 43609847, Stop 44211442
Child Probe 3' RD, Chr10
Start 43465309, Stop 43609540