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SureFISH ALK BA P200

SureFISH ALK BA P200

SureFISH ALK BA P200 is recommended for the detection of rearrangements involving the ALK gene by fluorescence in situ hybridization (FISH). The probe can be used on formalin-fixed, paraffin-embedded tissue sections.

SureFISH ALK BA P200 consists of two child probes (3’ and 5’ probes), each labeled in a different color (Cy3 and FITC). The child probes are designed to hybridize on opposite sides of the translocation break point for the ALK gene. Following a translocation, the signals are “broken apart” and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).

Child Probe 5' GR, Chr2
Start 29446949, Stop 30045655

Child Probe 3' RD, Chr2
Start 29146786, Stop 29446528

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