6560 Ion Mobility LC/Q-TOF
The system features innovative electrodynamic ion funnel technology to dramatically improve sensitivity while maintaining an attractive low field drift tube design. This allows you to directly measure accurate collision cross sections (CCS) and preserve labile targets. Whether you are looking to create a more comprehensive profile of metabolomics samples, characterize complex polymeric mixtures, or understand structural changes in biomolecules, ion mobility mass spectrometry provides access to new information.
- Quadrupole Time of Flight LC/MS
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Product Details
- First-principle based collision cross-section measurement and accuracy without standards.
- Utmost separation capacity, combining UHPLC, ion mobility, and high resolution mass spectrometry.
- Better separation of complex isobaric classes such as lipids and glycans.
- In-depth characterization of structural conformations and isomeric compounds.
- Conservation of structural fidelity of molecules in the gas phase using the low-energy drift tube design.
- Multiplexing for substantially increased sensitivity and dynamic range, with enhancement of one order of magnitude.
- Ion mobility resolution of up to 200 in full spectra can be achieved via postprocessing with the Agilent high resolution demultiplexing ( HRdm 2.0) software.
- Collision-induced unfolding (CIU) for quantitative structural analysis of proteins includes in-source activation for induced fragmentation of molecules.
- Up to 5 Hz acquisition rate can be used without compromising resolution for UHPLC compatibility.
- Utilizes Agilent VacShield for vent-free capillary removal.
| In-spectra Dynamic Range |
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| Ion Mobility Resolution (FWHM) |
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| Ion Source |
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| MS Acquisition Rate |
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| MS Mass Accuracy (positive) |
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| MS Sensitivity (positive) |
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| MS/MS Acquisition Rate |
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| MS/MS Mass Accuracy (positive) |
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| Quad Resolution (FWHM) |
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| Quadrupole Isolation Mass Range |
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| Software Platform |
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| Supported Software Add-Ons |
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| TOF Mass Range |
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| TOF Mass Resolution (FWHM) |
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| Temperature Mass Stability |
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| Ventless Maintenance |
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Additional Technology and Software Capabilities for LC/Q-TOF
Agilent partners with selected companies who provide technologies and software that expand the core capabilities of the LC/Q-TOF portfolio. Learn more about additional capabilities and visit the compatibility matrix to see which ones are offered for your LC/Q-TOF!
Learn More- Key Literature
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The Agilent Ion Mobility Q-TOF Mass Spectrometer System
Agilent Ion Mobility Q-TOF delivers an added dimension of separation and provides accurate direct measurement of collision cross sections.
- Technical Overviews
- English
- 18 May 2021
- 1.59 MB
HRdm 2.0: Maximize Your IM Resolution Without Sacrificing Drift Range, Mass Range, or Data Acquisition Time
In 2021 Agilent announced HRdm 2.0 enabling researchers to obtain drift resolutions as high as 250 on an LC time scale, while continuing to obtain accurate, precise, and reproducible CCS values. HRdm 2.0, combines demultiplexing and deconvolution into an easy-to-use tool yielding previously unattainable performance on a commercial drift tube instrument.
- Technical Overviews
- English
- 22 Mar 2022
- 551.66 KB
- Application Notes
- Brochures
- Case Studies
- Flyers
- Posters
- Technical Overviews
Agilent Wins Multiple 2022 Scientists' Choice Awards at ASMS
Based on votes from scientists around the world, the Agilent 6560C Ion Mobility LC/Q-TOF was awarded the Best New Spectroscopy Product of 2021. Additionally, Agilent won the Analytical Science Video Interview of the Year award for its customer video interview with Matt Campion from Airborne Honey, on Robust analysis for ensuring honey authenticity.
- 22 Jun 2022
Agilent Announces Inspirational LC/TQ and LC/Q-TOF Mass Spectrometry Solutions at ASMS 2023
Agilent Technologies announced two new liquid chromatography mass spectrometry systems (LCMS), the Agilent 6495D LC/TQ and the Agilent Revident LC/Q-TOF. Facilitating the high-end performance of the Revident LC/Q-TOF, Agilent is also announcing the new Agilent MassHunter Explorer Profiling software and the new Agilent ChemVista library manager software.
- 05 Jun 2023
Videos
Structural insights into Biomolecules by Ion Mobility MS
Gain insight into protein structural changes via Collision Induced Unfolding (CIU) and separation of in-class isomers via high-resolution demultiplexing (HRdm).
Development of a New Uniform-Field Ion Mobility Q-TOF MS
How the development of a new ion mobility Q-TOF can increase the peak capacity and separation resolution to facilitate high-throughput analysis of biomolecular mixtures.
- Support
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MassHunter Data Acquisition for LC/TOF and LC/Q-TOF Familiarization Guide
This guide teaches you how to use your MassHunter Data Acquisition for Agilent LC/TOF or LC/Q-TOF system.
- Familiarization Checklists
- English
- 13 Jul 2023
- 4.44 MB
MassHunter Workstation 11.0 for LC/TOF and LC/Q-TOF Installation Guide
This book provides instructions to install the MassHunter Workstation software in these configurations: • Workstation (standalone, no content management) • Networked Workstation (networked, with content management on separate server)
- Installation Guides
- English
- 13 Jul 2023
- 967.69 KB
MassHunter Networked Workstation Functional Design Specifications
This document contains the Functional Design Specifications for your Agilent MassHunter Networked Workstation system.
- Specifications
- English
- 17 Nov 2022
- 13.06 MB
- FAQs
- Quick Reference Guides
- Site Preparation Checklists
- Supplemental Information
- User Manuals