Neurofilaments belong to the family of intermediate filaments and are structural elements of the neuronal cytoskeleton in an interconnection with actin microfilaments, microtubules and other intermediate filaments. This antibody labels neurons (axons) of the central and peripheral nervous system, and is a useful aid for classification of tumors with neuronal differentiation.
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Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Frozen
Formalin
HIER
Clone
2F11
Code Number
M0762
Immunogen
Neurofilament isolated from normal adult human brain (6). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 15 mmol/L NaN3.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
In immunoblotting, the antibody reacts with the 70 kDa subunit of neurofilament (6). In immunohistochemistry, the antibody specifically labels neuronal cells (6). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.