Neurofilaments belong to the family of intermediate filaments and are structural elements of the neuronal cytoskeleton in an interconnection with actin microfilaments, microtubules and other intermediate filaments. This antibody labels neurons (axons) of the central and peripheral nervous system, and is a useful aid for classification of tumors with neuronal differentiation.
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
2F11
Immunogen
Neurofilament isolated from normal adult human brain (6). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions
Autostainer Link 48
Species
Mouse Anti-Human
Specificity
In immunoblotting, the antibody reacts with the 70 kDa subunit of neurofilament (6). In immunohistochemistry, the antibody specifically labels neuronal cells (6). See package insert for reference(s).
