The antigen recognized by this antibody is present in normal human hepatocytes and is conserved in a majority of hepatocellular carcinomas (1). The antibody is a useful aid for classification of hepatocellular carcinomas. The antibody does not label other tumors, except for some rare tumors of gastrointestinal origin.
This product is not available for purchase by the general public.
Product Details
Features
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
OCH1E5
Code Number
IR624
Immunogen
Formalin-fixed, failed human allograft liver that was mechanically disrupted (2). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions
Autostainer Link 48
Species
Mouse Anti-Human
Specificity
The antibody labels an antigen that seems to be localized to the mitochondrial fraction of liver homogenates (2). See package insert for reference(s).
1. Minervini MI, Demetris AJ, Lee RG, Carr BI, Madariaga J, Nalesnik MA. Utilization of hepatocyte-specific antibody in the immunocytochemical evaluation of liver tumors. Mod Pathol 1997,10:686-92.