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ERCC1 (Autostainer Link 48)

Lymphoid tissue

ERCC1 (Autostainer Link 48)

Clone 4F9

Excision repair cross-complementing rodent repair deficiency-1 (ERCC1) is a ~33 kDa nuclear protein involved in the nucleotide excision repair pathway (NER). The NER pathway is utilized to repair DNA mutations that occur as a result of DNA damage from external compounds, environmental carcinogens and UV-light.

Antibodies to ERCC1 is a useful aid for classification of a variety of tumor types including non-small cell lung carcinoma, gastroesophageal carcinoma, urothelial carcinoma, bladder carcinoma, and head and neck squamous cell carcinoma.

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