Reacts with the 45 kDa protein corresponding to cytokeratin 18. The antibody labels a large number of simple epithelia, including many ductal and glandular epithelia. The antibody is a useful aid for classification of tumors of epithelial origin. In vascular tumors, the antibody may be a useful aid in the classification of epithelioid hemangioendotheliomas.
This product is not available for purchase by the general public.
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
PCM 42, human breast carcinoma cell line (7). See package insert for reference(s).
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Autostainer Link 48
In Western blotting of cytokeratin preparations from BT 20 cells, the antibody labels a single band of 45 kDa corresponding to CK18 (7). In immunocytochemistry on human cultured cell lines, the antibody labels tumor cells of epithelial origin, whereas normal fibroblasts and tumor cells of non-epithelial origin such as glioma, melanoma and osteosarcoma, are not labeled (7). See package insert for reference(s).