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CD57 (Autostainer Link 48)

Hodgkin lymphoma (LP subtype)

CD57 (Autostainer Link 48)

Clone TB01

CD57 is expressed by subsets of NK cells and CD8+ lymphocytes, and by a small percentage of CD4+/CD45R0+ T lymphocytes in lymph node germinal centres. The number of CD57+ cells increases in some pathologies characterized by an imbalance of CD4/CD8 lymphocytes. Normal neuroectodermal cells and striated muscle also express CD57. Antibodies to CD57 may be a useful aid for classification of T-cell large granular lymphocyte disorders, oligodendrogliomas and neuroendocrine tumors, and may also aid in the classification of lymphocyte predominant Hodgkin's lymphoma.

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