CD43 is an integral membrane protein typically expressed at high levels on all leucocytes, except most resting B lymphocytes. Antibodies to CD43 may be a useful aid for the classification of low-grade B-cell lymphomas and myeloid disorders.
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Autostainer Plus
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
KG1 cells (myeloblastic cell line).
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Dako Autostainer/Autostainer Plus
Western blotting and immunohistochemical reactivity of the antibody is identical with that of CD43-clustered antibodies. Additionally the antibody reacts strongly with COS-7 cells (monkey kidney cell line) transfected with the CD43 gene, while control cells transfected with the vector only are negative (4). The antibody causes rapid and vigorous aggregation among normal leukocytes and among T and myeloid/monocytic cell lines (5). See package insert for reference(s).