Alpha-1-fetoprotein (AFP) is a 70 kDa glycoprotein, synthesized by the cells of the embryonic yolk sac, fetal liver and fetal intestinal tract. Expression of AFP has been demonstrated in many hepatocellular carcinomas and in gonadal and extragonadal germ cells tumors, including yolk sac tumors. The antibody is a useful aid for classification of neoplastic liver diseases, yolk sac tumors and mixed germ cell tumors.
This product is not available for purchase by the general public.
Product Details
Features
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
Polyclonal
Code Number
IR500
Immunogen
Alpha-1-fetoprotein isolated from human cord serum.
Reagent Provided
Ready-to-use polyclonal rabbit antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions
Autostainer Link 48
Species
Rabbit Anti-Human
Specificity
The antibody reacts with human alpha-1-fetoprotein. Traces of contaminating antibodies have been removed by solid-phase absorption with human plasma proteins. In indirect ELISA no significant reaction is observed with normal human plasma.