The GenetiSure Pre-Screen Complete Kit from Agilent is a cost-effective solution for rapid identification of DNA copy number variations and aneuploidies in human cell samples collected from embryo biopsies and single cell samples. The kit includes QIAGEN REPLI-g MDA whole genome amplification, providing highly uniform amplification across the entire genome, with minimal locus bias during amplification. The GenetiSure Pre-Screen microarrays have uniform, genome-wide probe coverage, with increased density on chromosomes 13, 18, 20, 21, 22 and X. The complete kit solution includes the new amp and labeling bundle and all components needed to amplify and label up to 48 single-cell samples to maximize workflow efficiency with any throughput.
For Research Use Only. Not for use in diagnostic procedures.
This guide contains information to run the Whole Genome Amplification, Labeling, and CGH Microarray Hybridization protocol for the GenetiSure Pre-Screen Kit.
Oligonucleotide Array-Based CGH for Genomic DNA Analysis - Enzymatic Labeling
For Blood, Cells, or Tissues (with a High Throughput option) Protocol
User Manuals
English
04 Mar 2020
4.63 MB
PDF
Featured References
Publications
Pinto D et al. Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants. Nat Biotechnol. 2011 May 8;29(6):512-20. doi: 10.1038/nbt.1852 [Application: General] Learn More
Alesi V et al. Easychip 8x15k: A New Tool for Detecting Chromosome Anomalies in Low Risk Pregnancies, Supporting and Integrating Standard Karyotype J Genet Syndr Gene Ther 7: 277. doi:10.4172/2157-7412.1000277 [Application: Prenatal] Learn More
Chau MHK et al. Characteristics and mode of inheritance of pathogenic copy number variants in prenatal diagnosis. Am J Obstet Gynecol. 2019 Nov;221(5):493.e1-493.e11. doi: 10.1016/j.ajog.2019.06.007. Epub 2019 Jun 14. [Application: Prenatal] Learn More