GenetiSure Postnatal Research Array (2x400K)
RUO
The GenetiSure postnatal research array allows simultaneous detection of copy number changes and copy neutral aberrations down to 2.5 Mb. Through the inclusion of exon-centric probes, the detection of aberrations associated with intellectual disability and congenital anomalies is maximized. The system can also be used in a wide range of postnatal array CGH research applications.
Updated CGH probe content targeted to regions of the genome known to be disease-associated can be easily sourced from the ClinGen/ISCA database.
Updated CGH probe content targeted to regions of the genome known to be disease-associated can be easily sourced from the ClinGen/ISCA database.
For Research Use Only. Not for use in diagnostic procedures.
Product Details
Features
- Maximize the detection of aberrations associated with intellectual disability and congenital anomalies with exon-centric probes.
- Single exon copy number detection for a clearer workflow.
- Covers disease-associated regions recommended by ClinGen/ISCA databases.
- 89% of the exon is covered with three or more probes during analysis.
- The median CGH probe spacing is approximately 9.8 KB overall.
- The system contains ~300,000 CGH probes and ~103,000 SNP probes.
- The probe standard 2x400 format can also be customized for other sizes and genes may be added or removed to further customize the array.
- Benefit from a complete workflow provided by a single supplier.
Featured References
- Publications
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- Pinto D et al. Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants. Nat Biotechnol. 2011 May 8;29(6):512-20. doi: 10.1038/nbt.1852 [Application: General] Learn More
- Alesi V et al. Easychip 8x15k: A New Tool for Detecting Chromosome Anomalies in Low Risk Pregnancies, Supporting and Integrating Standard Karyotype J Genet Syndr Gene Ther 7: 277. doi:10.4172/2157-7412.1000277 [Application: Prenatal] Learn More
- Chau MHK et al. Characteristics and mode of inheritance of pathogenic copy number variants in prenatal diagnosis. Am J Obstet Gynecol. 2019 Nov;221(5):493.e1-493.e11. doi: 10.1016/j.ajog.2019.06.007. Epub 2019 Jun 14. [Application: Prenatal] Learn More
- Ribeiro et al. Upper aerodigestive tract carcinoma: Development of a (epi)genomic predictive model for recurrence and metastasis. Oncol Lett. 2020 May;19(5):3459-3468. doi: 10.3892/ol.2020.11459. Epub 2020 Mar 12 [Application: Cancer] Learn More
- Kaur et al. Clinical impact of chromothriptic complex chromosomal rearrangements in newly diagnosed multiple myeloma. Leuk Res. 2019 Jan;76:58-64. doi: 10.1016/j.leukres.2018.12.005 [Application: Cancer] Learn More
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