5200 Fragment Analyzer system for DNA and RNA quality control
5200 Fragment Analyzer System
The 5200 Fragment Analyzer system performs DNA and RNA quality control (QC) for a broad range of samples, including gDNA, small RNA, cfDNA, large DNA fragments, total RNA, and mRNA. The diversity of sample types that these systems can separate make these instruments ideal for individualized workflows, including library QC for next generation sequencing (NGS) and mRNA integrity analysis in mRNA vaccine production workflows.
- Fragment Analyzer Systems
Product Details
- Low- to mid-throughput separation – Analyze 12 samples per run using parallel capillary electrophoresis
- Unattended walk-away operation – Load up to three 96-sample microplates, no further user interaction is required
- Optimized for speed or resolution – Choose from three different capillary array lengths for either fast or high-resolution analysis
- Minimized instrument preparation time – Reduce the time needed for instrument setup with no daily array handling requirements and room-temperature-stable reagents
- Broad assay portfolio – Analyze samples ranging from gDNA, NGS libraries, and DNA fragments to total RNA, small RNA, and IVT mRNA vaccines all on one platform
- High-resolution separation – Achieve separation resolution as good as 3 bp from fragments under 300 bp
- Objective quality assessment – Qualify your samples using quality metrics for RNA (RQN) and genomic DNA (GQN)
- Seamless switching between applications – Load two different gels into the instrument to use different kits within one system setup
- Comprehensive compliance services – Qualify instruments by IQ/OQ services for use in GMP environments
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- Key Literature
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Suitability Testing for IVT mRNA Analysis Using Agilent Fragment Analyzer Systems
This application note provides an example of a suitability study using the Agilent Fragment Analyzer system.
- Application Notes
- English
- 01 Aug 2025
- 750.77 KB
Quality Control in the PacBio HiFi Whole Genome Sequencing Library
Accurate and reliable next-generation sequencing (NGS) results rely on starting with high-quality samples.
- Application Notes
- English
- 02 Jul 2025
- 1.77 MB
CQA Assessment of LNP-Encapsulated IVT mRNA Using Agilent Fragment Analyzer Systems
This technical overview provides examples of CQAs for IVT mRNA, such as size, concentration, purity, and integrity, that can be addressed by the Agilent Fragment Analyzer system.
- Technical Overviews
- English
- 06 Mar 2025
- 381.88 KB
- Application Notes
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Dr. Kaat Leroy
Lab manager of the Functional Epigenetics Laboratory, KU Leuven
"The main advantage for us is, indeed, that we can go fast when needed with three plates that can be loaded at the same time without even having to be there"
View MoreSophie Wehren
QC Development Project Lead, Kaneka Eurogentec
“We know it [the Fragment Analyzer system] is a robust solution for mRNA, and we would be happy to use it in other applications.”
View MoreDr. Wassim Lakhal
Team leader in the Equipments Department, Hologenic Diagenode
“I was personally amazed by the instrument’s flexibility. The way it [the Fragment Analyzer system] works, the precision, the high resolution. And the fact that you can load all your samples on many plates and even remove samples while the device is running.”
View More