Mass Profiler Professional Software

Agilent Mass Profiler Professional (MPP) software is a chemometrics platform for exploiting the high information content of MS data and can be used in any MS-based differential analysis to determine relationships among two or more sample groups and variables. It provides advanced statistical analysis and visualization tools for GC/MS, LC/MS, CE/MS, and ICP-MS data.
MPP is the only platform that provides integrated identification/annotation of compounds and integrated pathway analysis for metabolomics and proteomics studies. Automated sample classification is enabled by the available MassHunter Classifier tool, which revolutionizes MS-based qualitative analysis of unknown samples.

Allows differential analysis of two or more sample sets from one or multiple MS analysis platforms in a single project
Designed for both mass spectrometrists and statisticians, with guided and advanced workflows
Provides comprehensive statistical tools including ANOVA, PCA, volcano plots, hierarchical trees, SOMs, and multiple methods for class prediction
Generates inclusion list for subsequent MS/MS-based analyses to facilitate identification of compounds of interest
The ID Browser allows integrated identification and annotation of compound using LC/MS Personal Compound Databases (METLIN, Pesticides, Forensics) and GC/MS libraries (NIST and Agilent Fiehn Metabolomics)
MPP integrates well with MassHunter Profinder, Lipid Annotator and Classifier – find out more under How It Works
Method automation capability in MPP enables the user to automate the complete analysis steps including experiment creation, normalization, data filtering and statistical analysis
Allows import and export of data in several formats to further extend and customize statistical analysis and visualization capabilities using R-Scripts
MPP 15.0 integrated with GeneSpring GX allows the correlation of pathways between MS (metabolomics, proteomics) and genomics data (microarray and NGS) in one project, enabling true integrated biology studies

Overview

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How it works

MassHunter Profinder

MassHunter Profinder is a fast, batch-processing feature extraction software for differential analysis that supports data from Agilent GC/MSD, GC/Q-TOF, LC/TOF and LC/Q-TOF instruments. Profinder finds more compounds using Agilent’s unique recursive untargeted feature-finding algorithm. Profinder also supports qualitative flux analysis using a cutting-edge extraction algorithm for targeted stable label isotope data mining that includes background correction and isotopologue incorporation display.

MassHunter Classifier

MassHunter Classifier can be used for easy classification of unknown samples (e.g. comparison of the quality of different batches or classes of olive oil). MassHunter Classifier, allows LC/MS and GC/MS users to transform fingerprinting strategies, developed via Agilent MassHunter Profinder and Mass Profiler Professional into automated sample classification reports that present actionable results to an analyst. The application empowers users to run classification analysis at the touch of a button.

MassHunter Lipid Annotator

Agilent MassHunter Lipid Annotator is a software to support lipidomics workflow.
Agilent MassHunter Lipid Annotator software is built on an algorithm that uses probability theory and least squares fit to annotate lipids based on an updated in silico MS/ MS database for Q-TOF CID fragmentation modeled from lipid standards for each lipid class. The Lipid Annotator software uses iterative MS/MS data to make rapid and accurate lipid annotations, and automatically generate PCDL spectral libraries with RT information.

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Genomics Software & Informatics