Software Status Bulletin

Preface
-------------------------
This Software Status Bulletin (SSB) documents all known problems in the software
product designated above. The SSB is derived from Known Problem Reports (KPR)
which result from user problems that have been classified as documentation
problems or software defects. When a KPR is written, an identifying number is
assigned to it, and the KPR is added to the next edition of the SSB.

User inputs that have been classified as Enhancement Requests are not documented
in the SSB. User problems that have been submitted, but that have not been
classified by the time the SSB is generated are not included in the SSB.

How to use the SSB
-------------------------
When you experience a problem with a product, first check this SSB to see if the
problem has been reported already, and if there is a temporary workaround
available for the problem, or if the problem has already been fixed by a new
revision. If the problem is not listed in this SSB then you may wish to report
it to the Response Center or to your field support representative.

To determine if your problem is documented in this SSB, first look in the
Keyword Index section of the SSB. Under each keyword is a listing of one-line
descriptions of related KPRs. If any of these sound like yours, locate the KPR
# in the Known Problem Reports section of the SSB, and read the full KPR. The
KPRs in the Known Problem Reports section are sorted by KPR #.

There are two sections in the SSB:
Keyword Index: This index is categorized by keyword. For each KPR there is a
brief description and a KPR #. A KPR may be associated with more than one
keyword.

Known Problem Reports: This section contains KPRs, with all the available
information relevant to the problem. KPRs in this section are sorted by KPR #.

Keyword Glossary

Keyword Index

Keyword: Data Analysis

KPR#:311593 After analysis of samples result data are not available in TapeStation Analysis software

Keyword: Functionality

KPR#:153817 TapeStation software not working after specific rearrangements of reporting sections
KPR#:806126 Inconsistent ladder display between single and multi-ScreenTape runs.

Keyword: Installation

KPR#:262409 Installation or update of TapeStation software errors if instrument is connected
KPR#:265467 After update/installation of the TapeStation software the Analysis software does not open automatically
KPR#:753853 Camera Error after software upgrade to Rev 5.1
KPR#:800380 Fatal error during installation
KPR#:1139091 Fatal error during installation

Keyword: Instrument Control

KPR#:497011 TapeStation system cannot connect due to issues with the USB to serial converter driver
KPR#:509453 TapeStation Controller software stops working during runs due to camera connection issues.
KPR#:687470 Reestablishing of lost connections eventually don't happen automatically.

Keyword: Performance

KPR#:237944 TapeStation software not working in combination with 2100 Expert Security Pack installed.
KPR#:255049 TapeStation instrument lid button does not indicate a run abort request by blinking.
KPR#:350365 TapeStation Controller software termination after Electrode Cartridge change is executed twice in row
KPR#:473110 Electropherogram is shown in reversed orientation

Keyword: Reliability

KPR#:790799 Unexpected Software termination
KPR#:1139089 Unexpected Software termination

Keyword: Reports

KPR#:572557 Exported word reports contain truncated gel images TapeStation software

Keyword: Roles and Privileges

KPR#:1267603 The “import file” permission enables users to import and access any data file from the same Security Module system.
KPR#:1283206 The TapeStation Security Module default roles are reset when the Security Module service restarts with less than 5 roles in the database, overwriting any previous customization made to default roles.

Keyword: User Interface

KPR#:759559 Electrophoresis Current Leakage test printout lacks one graphic.

Keyword: Data Analysis

One-line Description:

After analysis of samples result data are not available in TapeStation Analysis software

Problem:

After sample run the TapeStation Analysis software is unable to open the recorded data file. Further, the recorded file is missing in the dedicated data folder location. This fail appears with very low frequency.

Temporary Solution:

The recorded file might be available in raw data format (*.901r) in a temporary folder of the application (C:\Users\<logged in user>\AppData\Local\Temp\) and as such is recoverable. Please attempt to open the respective raw data file by drag and drop to the TapeStation Analysis software. 
Else, please collect troubleshooting information (File > help > collect log files) in zip format and contact your local support representative for help. 

Fix Information:

TapeStation software revision 4.1 addressed a root cause and additionally mitigates this condition by populating dedicated instruction on how to rescue datafiles of affected runs. Please update to TapeStation software revision 4.1.

Keyword: Functionality

One-line Description:

TapeStation software not working after specific rearrangements of reporting  sections

Problem:

The sections of an analysis report might be customized to show up in a desired order. The section "Compress Report (PDF Only)" must not be moved away from its first position else an unexpected error occurs and the software cannot be restarted any longer.

Temporary Solution:

The reorder of the section "Compress Report (PDF Only)" must be avoided. To correct the suppressed startup of the software a dedicated folder, namely "%HOMEPATH%\AppData\Local\Agilent\TapeStation_Analysis_Soft_StrongName_<Strong Name>\<A.B.C.D>\user.config" should be deleted. As a consequence all user settings are lost but software is able to start.

Fix Information:

TapeStation software revision 4.1 handles the described situation, please update. 

Keyword: Functionality

One-line Description:

Inconsistent ladder display between single and multi-ScreenTape runs.

Problem:

The “insert ladder” behavior in the TapeStation Analysis software is not consistent between multi and single ScreenTape runs. When inserting an electronic ladder into a run file with multiple ScreenTape devices, the run ladder disappears. In contrast, for runs with a single ScreenTape device, the run ladder remains but is unassigned. 

Temporary Solution:

There is none.

Fix Information:

N/A

Keyword: Installation

One-line Description:

Installation or update of TapeStation software errors if instrument is connected

Problem:

The update or installation of TapeStation software was done while a TapeStation instrument was turned on and connected to the PC. Hence the drivers were not installed properly, and the unit remains non-operational. Typically, the installation procedure stops and performs a roll back of the installation with an error message. However certain circumstances might lead to situations with a not operational system which shows “Camera connection Errors” which cannot be circumvented.

Temporary Solution:

Turn instrument off or unplug the instrument. Uninstall TapeStation software through the Windows operating system (see “Add/Remove Programs” for Windows 7, “Uninstall Apps” for Windows 10), restart the computer and execute the TapeStation software setup.exe for installation again. The drivers for the instrument will be installed properly now.

Fix Information:

TapeStation software revision 4.1 handles the described situation. Even if the camera driver is modified at a later time point a newly implemented software startup check ensures the right camera driver is loaded.

Keyword: Installation

One-line Description:

After update/installation of the TapeStation software the Analysis software does not open automatically

Problem:

After update or installation of TapeStation software a dedicated issue might appear. In such case the Analysis software does not open automatically at the end of the very first analysis performed with the Controller software. This is a unique fail. No data is lost. Any further analysis is not affected.

Temporary Solution:

In such case open the Analysis software from the desktop icon. Browse to the data folder of the TapeStation files and drag and drop the generated raw datafile [resultdatafilename.r901] into the software for opening. The datafile will be reanalyzed, results are available for evaluation and reporting as intended. 
Datafolder location is by default: 
C:\Users\[logged_in_user]\Documents\Agilent\TapeStation Data

Fix Information:

Improved error handling was implemented in TapeStation software 4.1. Waiting for reoccurrence

Keyword: Installation

One-line Description:

Camera Error after software upgrade to Rev 5.1

Problem:

The camera driver Eye Ul-148xLE Series might have been not updated properly to rev 4.95 by the setup for unknown reasons which yields an error with the message "Error: Camera default detected". The driver version is identified best through the device manager (Universal Serial Bus Controllers, Properties). 

Temporary Solution:

After disconnection of the instrument and deinstallation another reinstallation of the TapeStation software on the same laptop reinstalls the camera driver. 

Fix Information:

n/a

Keyword: Installation

One-line Description:

Fatal error during installation

Problem:

For initial installations of TapeStation software 5.1 the setup stops if the used administrative account includes a space character in the name. In such case a message is displayed: "0x80070643 - Fatal error during installation."

Temporary Solution:

Log on and execute the setup while using an administrative account which has no space in its name. 

Fix Information:

n/a

Keyword: Installation

One-line Description:

Fatal error during installation

Problem:

For initial installations of TapeStation software 5.1 the setup stops if the used administrative account includes a space character in the name. In such case a message is displayed: "0x80070643 - Fatal error during installation."

Temporary Solution:

Log on and execute the setup while using an administrative account which has no space in its name. 

Fix Information:

n/a

Keyword: Instrument Control

One-line Description:

TapeStation system cannot connect due to issues with the USB to serial converter driver

Problem:

Upon start of the TapeStation Controller software scanning for connected instruments times out. In the device manager the entry one “USB serial converter” indicates the root cause with an exclamation mark. The “Update Driver” functionality within the properties is ineffective.

Temporary Solution:

Update the driver with FTDI Virtual Com Port Drivers VCD 2.12.28 (off-line installer) provided on the installation medium in the “Support Installer” folder. Alternatively visit https://www.ftdichip.com/Drivers/VCP.htm and select the current WHQL certified setup executable for a manual update.

Fix Information:

n/a

Keyword: Instrument Control

One-line Description:

TapeStation Controller software stops working during runs due to camera connection issues.

Problem:

The TapeStation Analysis software stops working during runs while ScreenTape device changes happen due to camera connection issues. An unexpected error appears, a simple software restart will yield a camera specific error. An instrument restart is required to clear the error as this reboots the instruments camera.

Temporary Solution:

In case the problem description applies do restart the instrument and afterwards restart the TapesStation Controller software. 

Fix Information:

n/a

Keyword: Instrument Control

One-line Description:

Reestablishing of lost connections eventually don't happen automatically.

Problem:

In certain cases, with two TapeStation instruments connected to one laptop (requires SW rev 5.1 or higher) and a loss of the connection to one instrument a situation happens which requires an instrument restart. Connections don't reestablish automatically as expected. The manual restart to enable reconnection can't be done immediately if the other instrument is in a run or undergoing diagnosis. The user has to wait to restart software.

Temporary Solution:

Avoid connection loss for a second instrument if another connected instrument is active in a run or diagnosis.

Fix Information:

n/a

Keyword: Performance

One-line Description:

TapeStation software not working in combination with 2100 Expert Security Pack installed.

Problem:

Both the TapeStation Controller and Analysis software do not start after installation on a computer with 2100 Expert Security Pack installed. Even after uninstallation of the 2100 Expert Security Pack and the secured area the TapeStation software remains inoperable. 
The TapeStation software is incompatible with an installation of the 2100 Expert Security Pack on the same PC. 
Above is in contrast to the general compatibility of the regular 2100 Expert software (DNA, RNA, Protein licenses). Be aware: TapeStation software and 2100 Expert SW might be co-installed but not co-executed.

Temporary Solution:

n/a

Fix Information:

Improved error handling was implemented in TapeStation software 4.1.

For administrators and IT experts the following work-around might be applied: 
1.) copy the "machine.config" from the first directory [C:\Windows\Microsoft.NET\Framework64\v4.0.30319\Config ]
2.) remove and backup elsewhere the "machine.config" file from the second directory [C:\Windows\Microsoft.NET\Framework\v4.0.30319\Config] 3.) Replace the "machine.config" in the second folder by a copy from the first directory.
In case the problem description applies but above instructions are uneffective do re-imaging of your computer or set up its operating system again. You might use the recovery media shipped with the system in case of Agilent provided bundle laptops. Execute the TapeStation software setup.exe for a new and unaffected installation.

Keyword: Performance

One-line Description:

TapeStation instrument lid button does not indicate a run abort request by blinking.

Problem:

The lid button of a TapeStation instrument is supposed to indicate by blinking if a user attempted to abort an analysis. This visualization is inconsistent dependent on aborting a run via the TapeStation Controller software or via the instrument itself.

Temporary Solution:

None. Be aware: The lid button starts blinking if a user tries to open the lid manually. In this case a message is displayed in the Controller software. If the abort attempt is initiated via the Controller software the bespoke message appears but instrument lid doesn’t blink.

Fix Information:

TapeStation software revision 4.1 handles this condition correctly, please update.

Keyword: Performance

One-line Description:

TapeStation Controller software termination after Electrode Cartridge change is executed twice in row

Problem:

After self-PM is done and Electrode Cartridge is removed and a second Electrode Cartridge is reinserted into the instrument TapeStation Controller software aborts. It is a minor incidence. The instrument i not damaged. No data is lost. A restart of the system clears the error.

Temporary Solution:

After each Electrode Cartridge exchange the instrument and TapeStation Controller software should be restarted. 

Fix Information:

TapeStation software revision 4.1 handles this condition correctly, please update.

Keyword: Performance

One-line Description:

Electropherogram is shown in reversed orientation

Problem:

In the comparison context the electropherogram of an analysis is showing intensity values mirrored in negative direction. This fail appears with extremely low frequency depending on the sequence of merge and zoom activities.

Temporary Solution:

Close software, reopen the data files to merge and save desired composite files prior to zooming. 

Fix Information:

TapeStation software revision 4.1 handles the described situation, please update. 

Keyword: Reliability

One-line Description:

Unexpected Software termination 

Problem:

Replacing sample names with an empty string, meaning not any character, in TapeStation analysis software sample table might yield termination of the software. 

Temporary Solution:

Avoid inserting empty strings to sample description field.

Fix Information:

None

Keyword: Reliability

One-line Description:

Unexpected Software termination 

Problem:

Replacing sample names with an empty string, meaning not any character, in TapeStation analysis software sample table might yield termination of the software. 

Temporary Solution:

Avoid inserting empty strings to sample description field.

Fix Information:

None

Keyword: Reports

One-line Description:

Exported word reports contain truncated gel images TapeStation software

Problem:

Datafile reports created in *.docx format do not contain gel images for all samples but only for first lanes. The flaw appears only in case they are opened with recent Word version such as 2103 (Microsoft Office or Office 365) or higher. Opening the same file with previous Word versions show full gel images. Pdf reports from the datafile contain full gel images.

Temporary Solution:

Word reports only work for version below 2103 or the user has to use exclusively pdf reports. Alternatively the snapshot function can be used to paste the image into the Word export.

Fix Information:

n/a

Keyword: Roles and Privileges

One-line Description:

The “import file” permission enables users to import and access any data file from the same Security Module system.

Problem:

1)	Users with "import file" permission for one project can import data files from other projects from the same Security Module system, independent of their role assignments to those other projects.

2)	The import dialog and the audit trail do not disclose the previous project name of the imported data file, referring to the previous project as "name unknown".

Temporary Solution:

The workaround is to avoid granting the "import file" permission, which is given to the default Project Administrator role. This can be achieved by: 
	• Removing the "import file" permission from the default Project Administrator role.
	• Avoid creating new or customized project roles with the "import file" permission. 

Fix Information:

This is planned to be fixed in future versions.

Keyword: Roles and Privileges

One-line Description:

The TapeStation Security Module default roles are reset when the Security Module service restarts with less than 5 roles in the database, overwriting any previous customization made to default roles.

Problem:

All default roles (e.g., System Administrator, Technician, Reviewer, etc.) can be freely customized permission-wise. Additionally, some but not all default roles can be deleted.  
If default roles are customized and the number of existing default roles is inferior to five, then restarting the Agilent Security Module service (via PC reboot or via Windows Services) results in a reset of the default roles in the Security Module software, overwriting the customization made to default roles.

Temporary Solution:

Ensure that a minimum of 5 default roles exist in the Security Module software. 

Fix Information:

This is planned to be fixed in future versions.

Keyword: User Interface

One-line Description:

Electrophoresis Current Leakage test printout lacks one graphic.

Problem:

The Electrophoresis Current Leakage test from the hardware troubleshooting test suite shows only evaluated numbers but no graphs for leak current traces. The software interface from System Diagnostic shows the test results including the graphics.

Temporary Solution:

Do review of full test results including the graphics from System Diagnostic.

Fix Information:

None