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ABSTRACT |
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In this webinar Dr. John Connolly, Chief Scientific Officer from Tessa Therapeutics, will present a novel flow cytometry-based method to demonstrate the importance of metabolic change in memory T cell differentiation and highlight these factors as critical quality attributes of adoptive T cell therapy. A complex interaction of anabolic and catabolic metabolism underpins T cell polarization and memory differentiation. The capacity of these cells to respond and adapt to changing environments by metabolic reprogramming is crucial to their effector function. |
WHAT YOU WILL LEARN |
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A novel flow cytometry-based method that captures the metabolic state of immune cells by targeting key proteins and rates
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The use cell metabolomics, demonstrating the ability to simultaneously measure divergent metabolic profiles and dynamic remodeling in human T cells
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The identification of a T cell central memory subpopulation that shows unique glycolytic dependence and proinflammatory phenotype
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DATE |
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Tuesday, October 23, 2019 |
TIME |
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08:00 PDT (Los Angeles)
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11:00 EDT (New York)
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16:00 BST (London)
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Register for the webinar now >> |
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For Research Use Only. Not for use in diagnostic procedures.
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