Hybridization techniques are used to localize and identify specific nucleic acid sequences. Initially used as a research tool, the development of non-radioactive probe labeling and detection systems has made this technology available to a wide variety of routine applications. Traditionally either cloned probes or synthesized oligonucleotide probes have been used for hybridization. We successfully introduced the peptide nucleic acid (PNA) probe, a nucleotide analogue capable of binding to DNA/RNA in a sequence-specific manner obeying the Watson-Crick base pairing rules.
In this section, you will find molecular pathology products which are not intended for FISH. The probes are either visualized using the GenPoint CSA System, In Situ Hybridization Detection System, PNA ISH Detection System or Chemiluminescent System for Nucleic Acid Blotting.