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Seahorse Metabolic Analyzers Enable Rapid, Quantitative Measurement of Cellular Bioenergetics

ABSTRACT Seahorse technology is based on measuring the rate of extracellular fluxes of analytes in the media surrounding cells. Seahorse assays enable quantification of cellular bioenergetics by measuring the two energy yielding pathways, mitochondrial respiration and glycolysis, in a sensitive and convenient microplate format. A cell’s ability to respond to increased energy, biosynthetic and redox demands are in a large part influenced by two fundamental pathways, mitochondrial respiration and glycolysis. Changes in these pathways are often triggered by the activation/regulation of specific metabolic signaling cascades such as the PI3K/Akt and mTOR pathways - directly linking cellular phenotype to bioenergetic status. By modifying these pathways, scientist and physicians can reprogram cellular metabolism, cell fate and ultimately, the outcome of disease.

IN THIS WEBINAR WE WILL DISCUSS
  • How researchers are employing Seahorse assays to visualize, manipulate, and understand normal and diseased states.

RECORDED January 21, 2016
TYPE On Demand
LANGUAGE English
View On-Demand Webinar Here >>


For Research Use Only. Not for use in diagnostic procedures.
PRESENTED BY
Presenter - David Ferrick Ph.D. David Ferrick Ph.D.
Chief Scientific Officer, Seahorse Bioscience