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Stem Cell Biology

Monitoring Stem Cell Metabolic Profiles and Switching

The reprogramming of somatic cells, such as fibroblasts, to a pluripotent state has a dramatic effect on the metabolic requirements of the cell, inducing a cancer-like (Warburg) metabolic shift from oxidative phosphorylation to glycolysis. There is increasing evidence illustrating that the metabolic shift in cells, such as induced pluripotent stem cells (iPSCs), has a significant importance in establishing pluripotent identity. Using Agilent Seahorse XF technology, researchers are uncovering the mechanisms involved in cellular reprogramming of stem cells.

Learn more about How XF Technology Works

Click to search either the Seahorse XF Publications Database or the Seahorse Cell Reference Database

For Research Use Only. Not for use in diagnostic procedures.