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Intact Protein Profiling

Find the Proteins That Differ Between Samples

Combining retention time with accurate mass from LC/MS data is a powerful approach for profiling compounds present in complex biological matrices. While such untargeted workflows have been applied to both metabolomic and proteomic samples, proteomics has been limited to peptide digests as feature extraction algorithms relied on resolved isotopes. Using Agilent’s unique large molecule feature extraction algorithm for extracting protein features allows this profiling approach to be applied to intact proteins. Protein features from large data sets can be subjected to statistical analysis and visualization at the protein level, thus enabling differential protein studies.

For Research Use Only. Not for use in diagnostic procedures.