OpenLab CDS

Unified chromatography and mass spectrometry data

Combines productivity, usability, and data integrity for fast reliable results

  • OpenLab CDS is a chromatography data system that enables productive, consistent, and secure analytical workflows. It unifies Agilent LC, GC, GC/MSD, LC/MSD, LC/TOF, and LC/Q-TOF, and, along with instruments from other vendors, in a single environment—streamlining training and standardizing the way work is performed across the lab.
  • Built-in tools simplify analysis, interpretation, and reporting, while technical controls help ensure work quality, strengthen records management, and enhance data security. OpenLab CDS is ideal for analytical labs that require the highest levels of data integrity across routine and advanced analytical workflows.
  • Data integrity and compliance – For laboratories that must follow requirements such as FDA 21 CFR Part 11, EU Annex 11, GAMP5 as well as ISO/IEC 17025 and EPA&#146s 40 CFR Part 160.
  • Application-specific software add-ons – Extend functionality or add additional capabilities with software add-ons such as Sample Scheduler, Multi-Attribute Method, MatchCompare, Deconvolution, GPC, ADFExport, and more.
  • Scalable architecture – Improve lab operations through centralization and get better access to instruments and information with a client/server configuration.
  • On-demand learning – Onboard new staff quickly and effectively with a wide variety of learning tools to improve knowledge and performance.
  • Automated software migration tools – Preserve result sets, methods, and user and instrument information from legacy ChemStation, ChemStation Edition, EZChrom Edition, and Galaxie CDS.
  • Automated qualification tool – Perform software qualification and verification tasks to ensure your software is operating as intended.
  • Flexible, remote access – Complete sample processing, review, and approval securely from home with virtualization, networking, and cloud solutions that make remote work simpler, safer, and more productive.

Confidence in Every Chromatography Result

Streamline chromatography workflows with data integrity at every step

A monitor displaying OpenLab CDS software

Overview

Transform your lab routine

Features and functionality that help labs work better, faster, and smarter.

Support laboratory growth

Connect laboratories, reduce data silos, and scale operations with confidence.

Laboratory with multiple liquid chromatography systems to support scaled operations.

Centralized lab operations

Connect instruments, data, methods, and users across laboratories to break down silos, streamline processes, and improve efficiency.

Learn about client-server benefits

Flexible deployment options

Deploy OpenLab CDS in the environment that best fits organizational requirements, from virtualized systems to cloud-based deployments.

See how it works

Person accessing laboratory software from a laptop in a remote location.

Take a closer look at OpenLab CDS

Click each hotspot to learn more about the key areas of OpenLab CDS. Use the button to navigate between the data analysis and data acquisition screen.

Data analysis

OpenLab CDS data analysis screen that displays chromatograms, injection results, and Peak Explorer

  1. Data processing

    Open and compare data across injection results quickly. Select the signals and traces you see to dial in on data you care about most.

  2. Chromatograms

    View processed chromatograms individually or overlaid.

  3. Injection results

    Displays results in tabular format.

  4. Peak explorer

    Spot trends, unexpected or missing peaks, retention time shift, integration problems, outliers, and artifacts. Diagnose instrument problems quickly by visualizing retention time trends.

  1. 20%, 24.5%
  2. 45.3%, 24.5%
  3. 45.5%, 54.37%
  4. 88.3%, 24.26%
Data acquisition

Data acquisition screen that displays a status bar, run queue, and workflow toolbar.

  1. Status bar

    Instantly know when the system is ready, injecting, or running.

  2. Run queue

    View the status of all your samples at a glance.

  3. Workflow toolbar

    Guides you through data acquisition tasks.

  4. Multi-technique data

    Combine chromatograms with UV or mass spectra

  5. Instrument status

    Updated in real time for all configured instrument models.

  1. 5.73%, 47.0%
  2. 19.5%, 27.7%
  3. 49.4%, 21.6%
  4. 62.2%, 56.0%
  5. 68.5%, 27.7%

See what's new in OpenLab CDS version 3.0

The latest OpenLab CDS release unifies LC/MS and LC/HRMS—bringing native Q‑TOF/TOF acquisition and high‑resolution workflows together in a single environment to strengthen data integrity and elevate QC confidence.

Explore the latest version

Gas chromatograph connected to data analysis software, showing chromatogram results on a computer screen with a history icon.

LC high-resolution MS, now built in

Integrate LC/MS and LC/HRMS workflows in a single data system to improve consistency and simplify operation across the laboratory.

Antibody assay data displayed in a chromatogram, highlighting automated peak identification and analyte detection.

MAM workflows for QC laboratories

Support LC/HRMS-based MAM workflows with guided analysis designed for QC laboratories, simplifying data review while leveraging OpenLab CDS data integrity controls.

Overlaid chromatographic peaks transformed into separate, resolved peaks, illustrating deconvolution of overlapping signals.

Enhanced GC/MS data review

Clearer review, less manual effort, and easier management of complex data.

OpenLab CDS Version 3.0

OpenLab CDS Version 2.8

OpenLab CDS Version 2.7

OpenLab CDS Version 2.6

Single sign-on for Windows domain users
yes
yes
yes
yes
Hot backup and restore
yes
yes
yes
yes
Method approval and obsolescence states
yes
yes
yes
yes
UV-based purification workflows
yes
yes
yes
yes
Guided integration optimization
yes
yes
yes
yes
Spectral smoothing for mass spectrometry
yes
yes
yes
yes
Reference chromatogram
yes
yes
yes
yes
Cloud deployments for data storage and administrative components
yes
yes
yes
yes
Network security encryption
yes
yes
yes
yes
Sample submission at instrument (Ad hoc mode)
yes
yes
yes
Centrally managed unattended printing
yes
yes
yes
Data Accessibility Tool add-on: Enables custom dashboards and advanced analytics
yes
yes
yes
Improved peak integration for large molecules
yes
yes
Sequence wait actions
yes
yes
UV library searching
yes
yes
Authorship restrictions for eSignature workflows
yes
yes
Supports US Pharmacopeia 2023 standards
yes
yes
Data flagging algorithms
yes
yes
Oligo Analysis Accelerator add-on: Purity profiling of oligonucleotides
yes
yes
MS Spectral Deconvolution add-on: Molecular weight confirmation
yes
yes
Advanced Sample Linking add-on: End-to-end sample traceability
yes
yes
MS-based purification workflows
yes
yes
Support for LC/TOF & LC/Q-TOF
yes
Integration with MassHunter BioConfirm Software
yes
Multi-Attribute Method (MAM) add-on: LC/MS peptide mapping
yes
Integration with MassHunter Qualitative Analysis Software
yes
Support for instrument tasks in sequence
yes
Enhanced compound management
yes
View ChemStation logs (audit trails)
yes
View EZChrom audit trails
yes

Specifications

See what our customers are saying

"The flexibility to adjust reports with custom calculations and alerts is unique to the reporting solution."

Keith Wilkins, PhD, Lead Analytical Chemist, Chemours

"[OpenLab CDS] is a robust and easy-to-use system. Excellent in reporting."

Gianfranco Brendolan, Owner and CEO, SGB Consultoria Quimica Ltda.

"Managers and analysts are more focused on science and quality throughput, as analysis that used to take days to hours is now completed in minutes."

Jayakumar A V, Executive Vice President, Ajanta Pharma

"I would definitely recommend OpenLab CDS to my colleagues. It offers seamless integration of new equipment into an ever-expanding laboratory."

Damian Connolly, Senior Analytical Scientist, APC

"OpenLab CDS brought instrument control to the next level."

Principal Investigator, Small Business Industrial Manufacturing Company

"OpenLab CDS is the favourite software in our lab. Everyone enjoys working with OpenLab CDS, which makes people happy."

Lab Technician, Educational Institution

Documents & support

Applications and industries

Petrochemical engineer working at an oil and gas refinery plant industry factory.

OpenLab CDS for Energy and Chemicals

OpenLab CDS is designed for the unique QC testing requirements of energy and chemical laboratories. Built-in support for ASTM and other standardized methods, industry-specific calculations, advanced reporting, and automated sample management help streamline routine testing workflows. Secure data management, centralized administration, and scalable deployment options simplify operations while supporting laboratory growth.

Explore more

Scientists in a pharmaceutical lab using a tablet to analyze data

OpenLab CDS for Pharma and Biopharma

OpenLab CDS is built for the rigorous demands of pharma and biopharma labs. It ensures compliance with FDA 21 CFR Part 11 and EU Annex 11 and simplifies workflows for method development, validation, and routine analysis. Advanced data integrity and secure audit trails protect your results, while flexible deployment options enable seamless integration across instruments and sites.

Frequently asked questions

What’s new in the latest release of OpenLab CDS?

The latest release of OpenLab CDS, version 3.0, brings native Q‑TOF/TOF acquisition into the software you trust—unifying LC/MS and LC high‑resolution MS workflows in a single, consistent environment. It also introduces key enhancements for single‑quadrupole GC and LC workflows to make daily analyses easier and more reliable.

What instruments are supported in OpenLab CDS?

See the complete list of supported instruments in OpenLab CDS.

What are the system requirements for OpenLab workstations?

See minimum requirements for Agilent OpenLab workstations including PC and network specifications, and operating systems.

Can OpenLab CDS be deployed in the cloud?

Labs can now leverage cloud technology when deploying OpenLab CDS so they can scale quickly and better protect their vital data. We have supported deployments of OpenLab CDS and ECM XT on Amazon Web Services and Microsoft Azure.

Can I upgrade to the newest version of Windows when it is released by Microsoft?

We recommend waiting to upgrade to new versions of Windows until we've fully tested the new version. See more details

Is OpenLab CDS supported with a Long-Term Servicing Channel (LTSC) version of Microsoft Windows?

While OpenLab CDS is mainly used with standard Semi-Annual Service Channel (SAC) versions of Windows included with most personal computers, Agilent does test and support the LTSC version.

What is a feature pack and what does it include?

Find detailed information about OpenLab CDS feature packs, including their contents and the naming conventions used.

What ASTM test methods are supported in OpenLab CDS?

See list of supported ASTM methods in OpenLab CDS version 2.7 and above.

How do I generate a license?

See the process for generating a permanent license file in SubscribeNet for OpenLab CDS software products.

style

Advance your lab with technical training

OpenLab CDS Webinar Series

Join our OpenLab webinar series for expert tips, best practices, and insights into new advanced features.

webinarType
Webinar
duration
type
Virtual instructor-led, on demand
cost

Three winning arguments to get management approval for an OpenLab CDS upgrade

Getting management approval for an OpenLab CDS upgrade is not always easy. Learn winning arguments to get approval for an OpenLab CDS upgrade in your lab.

webinarType
Webinar
duration
type
Self-paced course
cost

Data integrity webinars and podcasts

Series of webinars to help prepare for regulatory examinations. Stay informed about the latest FDA and global enforcement trends to stay compliant.

webinarType
Webinar
type
Self-paced course

Resources and services for success

Access training, validation, and expert resources to maximize the value of OpenLab CDS.

Person working on a laptop and writing in a notebook at a desk.

OpenLab CDS tutorials

Learn how to use OpenLab CDS with quick video tutorials that guide you through essential tools and workflows.

See tutorials

People seated in a classroom using laptops during a presentation.

Effective onboarding

Train new staff quickly and get the most out of your software with self-guided learning tools.

Get started

Compliance consulting and validation

Accelerate compliance with expert-driven validation solutions designed to simplify regulatory readiness.

Get expert guidance

Instrument and software qualification

ACE-powered compliance solutions help labs meet USP <1058> and ISO/IEC 17025 requirements across the full instrument lifecycle.

See compliance solutions

Automate software verification

Perform verification tasks to confirm that the software is operating as intended.

Explore test services

Explore the analytical software suite

Software support and resources

Line drawing of a shield with a checkmark in the center used mainly in the Support block

Get support from our technical experts driving lab performance and reliability

World-class team of experts dedicated to you. Hand selected from across the globe, each bringing a wealth of experience and expertise to help you solve your issue quickly and efficiently.

Outline of a group of people representing a community

Explore the Agilent Software Users Community

Licensing

Manage your software licenses and downloads.

Software Service Desk

Submit a support request or check the status of your request.

Software lifecycle policy

View lifecycle status and support timelines for OpenLab software versions.

Software status bulletin

Check the status bulletin for documented issues related to OpenLab software products.