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The deciphering of the human genome has ushered in a new scientific era where the complexity of biological systems can be systematically evaluated. Technology enabling the simultaneous measurement of the expression of all known genes in a cell is becoming ubiquitous in today’s research environment. As a leading solution provider in the area of gene expression microarray technology, Agilent is helping solve the challenging questions posed by the world’s leading research organizations.
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Dual-Mode Gene Expression | | | The process whereby information encoded in a gene is transcribed into mRNA is called gene expression. To identify and characterize this expression, Agilent has developed an open platform using DNA oligo microarrays, optimized reagents and hardware. | | | | | | |
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Oligo aCGH | | | Microarray-based Comparative Genomic Hybridization (aCGH) is a powerful technique used to identify and characterize DNA copy number changes (i.e. gains and losses), which are commonly found in cancer and many developmental abnormalities. | | | | | | |
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miRNA | | | MicroRNAs (miRNAs) are small single-stranded non-coding RNAs thought to modulate the expression of over one-third of human genes. They may rival transcription factors in modulating genes and are involved in development, proliferation and differentiation, and apoptosis. | | | | | | |
| | ChIP-on-chip | | | Agilent has introduced a ChIP-on-chip microarray solution that extends beyond gene expression to explore gene regulation. The technology, also known as location analysis, provides insight into key mechanisms of embryonic stem cells and illnesses such as cancer, cardiovascular disease, and central nervous system disorders. | | | | | | |
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DNA Methylation | | | DNA methylation is an epigenetic biological mechanism that regulates genes. Agilent’s DNA methylation microarrays allow researchers to monitor and study the role of methylation events in cancer, gene silencing, and human disease.
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GeneSpring Analysis Platform | | | The Agilent GeneSpring Analysis Platform is specifically developed to answer biological questions at the intersection of genomics, genetics, proteomics, and biomarker screening. Designed to integrate data and results from multiple applications, the platform provides comprehensive statistical analysis, data mining, and visualization tools to answer a wide range of research questions. | | | | | | |
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eArray and Custom Arrays | | | eArray, Agilent’s free online array design tool, gives you the power to create your own custom microarrays. Upload your own probes, reference one of Agilent’s probe databases, or use Agilent probe design tools to create the microarray design that meets your research needs | | | | | | |
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