Dako White Paper Outlines High-Quality Staining Enabled by Its New Immunohistochemical Staining Principle

GLOSTRUP, Denmark, March 4, 2014

Dako, an Agilent Technologies company and worldwide provider of cancer diagnostics, has announced positive findings in a white paper on its new, groundbreaking Dynamic Gap IHC staining technology.

Dako's newly released white paper shows that Dynamic Gap staining supports consistent, reproducible immunohistochemical (IHC) staining with no observed common artifacts, a major breakthrough for pathology labs worldwide. The new staining technology is available exclusively on the new Dako Omnis instrument for IHC and ISH.

The Dynamic Gap technology uses capillary force during reagent application while switching to continuous movement of reagents during reagent incubation and washes. This process increases the consistency of staining and prevents common staining artifacts, such as patchy staining, edge effects and air bubbles.

In developing the Dako Omnis solution, Dako focused on designing a system that could consistently provide high-quality, uniform staining over the entire tissue section. The Dynamic Gap technology used on the instrument has now shown that high-quality staining with very little staining intensity variation between slides, between instruments and on different days is possible.

Dako conducted four different tests using IHC staining on 2,136 tissue sections to examine the repeatability and reproducibility of the Dynamic Gap staining technology. Both intra- and inter-run variations showed very little variation in staining intensity. Also, there was virtually no visible difference in staining intensity no matter where on the glass slide the tissue sections were placed. No staining artifacts were encountered in any of the studied samples.

"Dynamic Gap staining raises the bar for immunohistochemical staining," said Britt Meelby Jensen, Dako general manager and Agilent vice president. "Dako Omnis was designed to improve the consistency of staining results and accuracy of patient diagnoses, and Dynamic Gap staining is an important part of this process."

About Dako - An Agilent Technologies Company

Dako, based in Denmark, is a global leader in tissue-based cancer diagnostics. Hospital and research laboratories worldwide use Dako's reagents, instruments, software and expertise to make accurate diagnoses and determine the most effective treatment for cancer patients. Dako became part of Agilent Technologies in 2012. Information about Dako is available at www.dako.com.


About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is the world's premier measurement company and a technology leader in chemical analysis, life sciences, diagnostics, electronics and communications. The company's 20,600 employees serve customers in more than 100 countries. Agilent had revenues of $6.8 billion in fiscal 2013. Information about Agilent is available at www.agilent.com.

On Sept. 19, 2013, Agilent announced plans to separate into two publicly traded companies through a tax-free spinoff of its electronic measurement business. The new company is named Keysight Technologies, Inc. The separation is expected to be completed in early November 2014.

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Contact:

Dako Products:
Dako Denmark A/S
+45 29 33 69 80
Victoria Wadsworth-Hansen

Dako Corporate:
Dako Denmark A/S
+45 25 46 10 83
Maia Fredtoft Søchting